Gene detail

SF4075

Histidine kinase, Classic

Shigella flexneri 2a str. 301 · GCF_000006925

ClassHKTypeClassicLength458 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000006925#SF4075Stable P2CS identifier used across views.
GenomeGCF_000006925Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Selected clusterHKOC_1858251Run 6 · 773 sequences · id 100% · cov 80% · representative
External referencesNP_709797.1 · MIST4 SF4075RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length458 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 458 aa (37.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa458 aa
HisKA: 237-299 aa (63 aa)1HATPase_c: 345-451 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
237-299 aa · 63 aa · 13.8% of protein
Raw tokenHisKA:237:0.00000000000108:299:63:64
2 HATPase_c#2
345-451 aa · 107 aa · 23.4% of protein
Raw tokenHATPase_c:345:6.45e-34:451:110:109
  • Raw architecture: HisKA:237:0.00000000000108:299:63:64#HATPase_c:345:6.45e-34:451:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000006925::NC_004337.2::G00031
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4220907-4223605Genomic interval covered by the local TCS group.
Context group IDGCF_000006925::NC_004337.2::G00031
Context members
SF4075SF4076
Partner locus tags
SF4075SF4076
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for NP_709797.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagSF4075Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_004337.2Sequence record reported by the local genomic context database.
Genomic interval4 220 907-4 222 283 nt1 377 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span4 220 907-4 223 605 ntGCF_000006925::NC_004337.2::G00031

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000006925::NC_004337.2::G00031

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004337.2All displayed genes belong to this local TCS context.
Neighborhood span4 220 907-4 223 605 nt2 699 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 220 907 nt4 223 605 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

SF4075GCF_000006925#SF4075
HKClassicCurrent focus

4 220 907-4 222 283 nt · Forward (+)

RefSeq NP_709797.1
SF4076GCF_000006925#SF4076
RRNtrC

4 222 280-4 223 605 nt · Forward (+)

RefSeq NP_709798.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1858251Run 6 · HK · 773 sequences
Representative sequenceGCF_000006925#SF4075The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1858251

Simplified PFAM architecture for HKOC_1858251

PFAM domain coverage: 168 / 458 aa (36.7%)

1 aa458 aa
HisKA: 238-300 aaHisKAHATPase_c: 346-450 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[238-300] | HATPase_c[346-450]
  • Domain count: 2
  • Matched identifier: HKOC_1858251
  • Positioned domains: HisKA 238-300 ; HATPase_c 346-450
Cluster members and taxonomy
Visualization

Representative gene: GCF_000006925#SF4075

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 198 214 · GCF_000006925
AssemblyASM692v2 · Complete Genomereference genome · haploid
Genome composition4 828 820 bp · 50,5% GCShigella flexneri 2a str. 301
Signal transduction countsGenes 54 · HK 25 · RR 29CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusShigella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Shigella

Related genes

Preview from the same derived genome key