Gene detail

SF1148

Histidine kinase, Classic

Shigella flexneri 2a str. 301 · GCF_000006925

ClassHKTypeClassicLength486 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000006925#SF1148Stable P2CS identifier used across views.
GenomeGCF_000006925Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Selected clusterHKOC_1567067Run 6 · 850 sequences · id 100% · cov 80% · representative
External referencesNP_707058.1 · MIST4 SF1148RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PhoQ_SensorHAMPHisKAHATPase_c
Protein length486 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage411 / 486 aa (84.6%)Merged over positioned domains only.
Domain description1 PhoQ_Sensor,1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa486 aa
PhoQ_Sensor: 10-189 aa (180 aa)1HAMP: 195-263 aa (69 aa)2HisKA: 272-330 aa (59 aa)3HATPase_c: 374-476 aa (103 aa)4
Domain-by-domain annotation4 items
1 PhoQ_Sensor#1
10-189 aa · 180 aa · 37.0% of protein
Raw tokenPhoQ_Sensor:10:6.12e-114:189:180:179
2 HAMP#2
195-263 aa · 69 aa · 14.2% of protein
Raw tokenHAMP:195:0.00000000381:263:69:69
3 HisKA#3
272-330 aa · 59 aa · 12.1% of protein
Raw tokenHisKA:272:0.000000461:330:59:64
4 HATPase_c#4
374-476 aa · 103 aa · 21.2% of protein
Raw tokenHATPase_c:374:1.29e-21:476:105:109
  • Raw architecture: PhoQ_Sensor:10:6.12e-114:189:180:179#HAMP:195:0.00000000381:263:69:69#HisKA:272:0.000000461:330:59:64#HATPase_c:374:1.29e-21:476:105:109
  • Domain description: 1 PhoQ_Sensor,1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000006925::NC_004337.2::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1189500-1191631Genomic interval covered by the local TCS group.
Context group IDGCF_000006925::NC_004337.2::G00006
Context members
SF1148SF1149
Partner locus tags
SF1148SF1149
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for NP_707058.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagSF1148Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_004337.2Sequence record reported by the local genomic context database.
Genomic interval1 189 500-1 190 960 nt1 461 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 189 500-1 191 631 ntGCF_000006925::NC_004337.2::G00006

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000006925::NC_004337.2::G00006

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004337.2All displayed genes belong to this local TCS context.
Neighborhood span1 189 500-1 191 631 nt2 132 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 189 500 nt1 191 631 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

SF1148GCF_000006925#SF1148
HKClassicCurrent focus

1 189 500-1 190 960 nt · Reverse (-)

RefSeq NP_707058.1
SF1149GCF_000006925#SF1149
RROmpR

1 190 960-1 191 631 nt · Reverse (-)

RefSeq NP_707059.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1567067Run 6 · HK · 850 sequences
Representative sequenceGCF_000006925#SF1148The current gene is the representative for this cluster.
PFAM architecturePhoQ_Sensor + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1567067

Simplified PFAM architecture for HKOC_1567067

PFAM domain coverage: 280 / 486 aa (57.6%)

1 aa486 aa
PhoQ_Sensor: 10-188 aaPhoQ_SensorHATPase_c: 375-475 aaHATPase_c
PhoQ_SensorHATPase_c
  • Simplified architecture: PhoQ_Sensor + HATPase_c
  • Raw architecture: PhoQ_Sensor[10-188] | HATPase_c[375-475]
  • Domain count: 2
  • Matched identifier: HKOC_1567067
  • Positioned domains: PhoQ_Sensor 10-188 ; HATPase_c 375-475
Cluster members and taxonomy
Visualization

Representative gene: GCF_000006925#SF1148

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 198 214 · GCF_000006925
AssemblyASM692v2 · Complete Genomereference genome · haploid
Genome composition4 828 820 bp · 50,5% GCShigella flexneri 2a str. 301
Signal transduction countsGenes 54 · HK 25 · RR 29CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusShigella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Shigella

Related genes

Preview from the same derived genome key