Gene detail

SF3990

Histidine kinase, Classic

Shigella flexneri 2a str. 301 · GCF_000006925

ClassHKTypeClassicLength457 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000006925#SF3990Stable P2CS identifier used across views.
GenomeGCF_000006925Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Selected clusterHKOC_1873336Run 6 · 681 sequences · id 100% · cov 80% · representative
External referencesNP_709717.1 · MIST4 SF3990RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length457 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage241 / 457 aa (52.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa457 aa
HAMP: 165-234 aa (70 aa)1HisKA: 238-299 aa (62 aa)2HATPase_c: 345-453 aa (109 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
165-234 aa · 70 aa · 15.3% of protein
Raw tokenHAMP:165:0.000000000000953:234:70:69
2 HisKA#2
238-299 aa · 62 aa · 13.6% of protein
Raw tokenHisKA:238:8.13e-17:299:63:64
3 HATPase_c#3
345-453 aa · 109 aa · 23.9% of protein
Raw tokenHATPase_c:345:7.06e-30:453:110:109
  • Raw architecture: HAMP:165:0.000000000000953:234:70:69#HisKA:238:8.13e-17:299:63:64#HATPase_c:345:7.06e-30:453:110:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000006925::NC_004337.2::G00030
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4118585-4120653Genomic interval covered by the local TCS group.
Context group IDGCF_000006925::NC_004337.2::G00030
Context members
SF3990SF3991
Partner locus tags
SF3990SF3991
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for NP_709717.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagSF3990Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_004337.2Sequence record reported by the local genomic context database.
Genomic interval4 118 585-4 119 958 nt1 374 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 118 585-4 120 653 ntGCF_000006925::NC_004337.2::G00030

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000006925::NC_004337.2::G00030

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004337.2All displayed genes belong to this local TCS context.
Neighborhood span4 118 585-4 120 653 nt2 069 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 118 585 nt4 120 653 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

SF3990GCF_000006925#SF3990
HKClassicCurrent focus

4 118 585-4 119 958 nt · Reverse (-)

RefSeq NP_709717.1
SF3991GCF_000006925#SF3991
RROmpR

4 119 955-4 120 653 nt · Reverse (-)

RefSeq NP_709718.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1873336Run 6 · HK · 681 sequences
Representative sequenceGCF_000006925#SF3990The current gene is the representative for this cluster.
PFAM architectureCpxA_peri + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1873336

Simplified PFAM architecture for HKOC_1873336

PFAM domain coverage: 293 / 457 aa (64.1%)

1 aa457 aa
CpxA_peri: 82-150 aaCpxA_periHAMP: 181-233 aaHAMPHisKA: 239-299 aaHisKAHATPase_c: 345-454 aaHATPase_c
CpxA_periHAMPHisKAHATPase_c
  • Simplified architecture: CpxA_peri + HAMP + HisKA + HATPase_c
  • Raw architecture: CpxA_peri[82-150] | HAMP[181-233] | HisKA[239-299] | HATPase_c[345-454]
  • Domain count: 4
  • Matched identifier: HKOC_1873336
  • Positioned domains: CpxA_peri 82-150 ; HAMP 181-233 ; HisKA 239-299 ; HATPase_c 345-454
Cluster members and taxonomy
Visualization

Representative gene: GCF_000006925#SF3990

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 198 214 · GCF_000006925
AssemblyASM692v2 · Complete Genomereference genome · haploid
Genome composition4 828 820 bp · 50,5% GCShigella flexneri 2a str. 301
Signal transduction countsGenes 54 · HK 25 · RR 29CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusShigella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Shigella

Related genes

Preview from the same derived genome key