Gene detail

SF3423

Histidine kinase, Classic

Shigella flexneri 2a str. 301 · GCF_000006925

ClassHKTypeClassicLength450 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000006925#SF3423Stable P2CS identifier used across views.
GenomeGCF_000006925Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Selected clusterHKOC_1957158Run 6 · 25240 sequences · id 100% · cov 80%
External referencesNP_709177.1 · MIST4 SF3423RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length450 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage236 / 450 aa (52.4%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa450 aa
HAMP: 160-229 aa (70 aa)1HisKA: 234-293 aa (60 aa)2HATPase_c: 334-439 aa (106 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
160-229 aa · 70 aa · 15.6% of protein
Raw tokenHAMP:160:0.0000000000438:229:70:69
2 HisKA#2
234-293 aa · 60 aa · 13.3% of protein
Raw tokenHisKA:234:0.00000000000328:293:63:64
3 HATPase_c#3
334-439 aa · 106 aa · 23.6% of protein
Raw tokenHATPase_c:334:2.33e-27:439:109:109
  • Raw architecture: HAMP:160:0.0000000000438:229:70:69#HisKA:234:0.00000000000328:293:63:64#HATPase_c:334:2.33e-27:439:109:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000006925::NC_004337.2::G00027
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3503802-3505870Genomic interval covered by the local TCS group.
Context group IDGCF_000006925::NC_004337.2::G00027
Context members
SF3423SF3424
Partner locus tags
SF3423SF3424
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for NP_709177.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagSF3423Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_004337.2Sequence record reported by the local genomic context database.
Genomic interval3 503 802-3 505 154 nt1 353 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 503 802-3 505 870 ntGCF_000006925::NC_004337.2::G00027

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000006925::NC_004337.2::G00027

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004337.2All displayed genes belong to this local TCS context.
Neighborhood span3 503 802-3 505 870 nt2 069 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 503 802 nt3 505 870 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

SF3423GCF_000006925#SF3423
HKClassicCurrent focus

3 503 802-3 505 154 nt · Reverse (-)

RefSeq NP_709177.1
SF3424GCF_000006925#SF3424
RROmpR

3 505 151-3 505 870 nt · Reverse (-)

RefSeq NP_709178.2

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1957158Run 6 · HK · 25240 sequences
Representative sequenceGCF_030346725#QT350_RS08200Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1957158

Simplified PFAM architecture for HKOC_1957158

PFAM domain coverage: 213 / 451 aa (47.2%)

1 aa451 aa
HAMP: 177-226 aaHAMPHisKA: 234-290 aaHisKAHATPase_c: 334-439 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[177-226] | HisKA[234-290] | HATPase_c[334-439]
  • Domain count: 3
  • Matched identifier: HKOC_1957158
  • Positioned domains: HAMP 177-226 ; HisKA 234-290 ; HATPase_c 334-439
Cluster members and taxonomy
Visualization

Representative gene: GCF_030346725#QT350_RS08200

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 198 214 · GCF_000006925
AssemblyASM692v2 · Complete Genomereference genome · haploid
Genome composition4 828 820 bp · 50,5% GCShigella flexneri 2a str. 301
Signal transduction countsGenes 54 · HK 25 · RR 29CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusShigella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Shigella

Related genes

Preview from the same derived genome key