Gene detail

SF3067

Histidine kinase, Classic

Shigella flexneri 2a str. 301 · GCF_000006925

ClassHKTypeClassicLength424 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000006925#SF3067Stable P2CS identifier used across views.
GenomeGCF_000006925Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Selected clusterHKOC_2225007Run 6 · 762 sequences · id 100% · cov 80% · representative
External referencesNP_708838.1 · MIST4 SF3067RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length424 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage224 / 424 aa (52.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa424 aa
HAMP: 164-232 aa (69 aa)1HisKA: 238-301 aa (64 aa)2HATPase_c: 327-417 aa (91 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
164-232 aa · 69 aa · 16.3% of protein
Raw tokenHAMP:164:0.00000155:232:70:69
2 HisKA#2
238-301 aa · 64 aa · 15.1% of protein
Raw tokenHisKA:238:0.00000000000668:301:64:64
3 HATPase_c#3
327-417 aa · 91 aa · 21.5% of protein
Raw tokenHATPase_c:327:0.00000000000000122:417:91:109
  • Raw architecture: HAMP:164:0.00000155:232:70:69#HisKA:238:0.00000000000668:301:64:64#HATPase_c:327:0.00000000000000122:417:91:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000006925::NC_004337.2::G00025
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3163038-3164968Genomic interval covered by the local TCS group.
Context group IDGCF_000006925::NC_004337.2::G00025
Context members
SF3066SF3067
Partner locus tags
SF3066SF3067
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for NP_708838.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagSF3067Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_004337.2Sequence record reported by the local genomic context database.
Genomic interval3 163 694-3 164 968 nt1 275 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span3 163 038-3 164 968 ntGCF_000006925::NC_004337.2::G00025

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000006925::NC_004337.2::G00025

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004337.2All displayed genes belong to this local TCS context.
Neighborhood span3 163 038-3 164 968 nt1 931 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 163 038 nt3 164 968 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

SF3066GCF_000006925#SF3066
RROmpR

3 163 038-3 163 697 nt · Forward (+)

RefSeq NP_708837.1
SF3067GCF_000006925#SF3067
HKClassicCurrent focus

3 163 694-3 164 968 nt · Forward (+)

RefSeq NP_708838.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2225007Run 6 · HK · 762 sequences
Representative sequenceGCF_000006925#SF3067The current gene is the representative for this cluster.
PFAM architecture2CSK_N + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2225007

Simplified PFAM architecture for HKOC_2225007

PFAM domain coverage: 294 / 424 aa (69.3%)

1 aa424 aa
2CSK_N: 23-157 aa2CSK_NHisKA: 237-301 aaHisKAHATPase_c: 327-420 aaHATPase_c
2CSK_NHisKAHATPase_c
  • Simplified architecture: 2CSK_N + HisKA + HATPase_c
  • Raw architecture: 2CSK_N[23-157] | HisKA[237-301] | HATPase_c[327-420]
  • Domain count: 3
  • Matched identifier: HKOC_2225007
  • Positioned domains: 2CSK_N 23-157 ; HisKA 237-301 ; HATPase_c 327-420
Cluster members and taxonomy
Visualization

Representative gene: GCF_000006925#SF3067

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 198 214 · GCF_000006925
AssemblyASM692v2 · Complete Genomereference genome · haploid
Genome composition4 828 820 bp · 50,5% GCShigella flexneri 2a str. 301
Signal transduction countsGenes 54 · HK 25 · RR 29CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusShigella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Shigella

Related genes

Preview from the same derived genome key