1 HAMP#1
182-247 aa · 66 aa · 7.2% of protein
Raw token
HAMP:182:0.00000000000133:247:66:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SF2799
Histidine kinase, Unorthodox
Shigella flexneri 2a str. 301 · GCF_000006925
ClassHKTypeUnorthodoxLength918 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000006925#SF2799Stable P2CS identifier used across views.
GenomeGCF_000006925Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_cResponse_regHpt
Protein length918 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage438 / 918 aa (47.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_c,1 Response_reg,1 HptSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa918 aa
Domain-by-domain annotation5 items
2 HisKA#2
293-357 aa · 65 aa · 7.1% of protein
Raw token
HisKA:293:1.12e-19:357:65:643 HATPase_c#3
404-519 aa · 116 aa · 12.6% of protein
Raw token
HATPase_c:404:7.48e-34:519:116:1094 Response_reg#4
670-781 aa · 112 aa · 12.2% of protein
Raw token
Response_reg:670:3.65e-36:781:112:1115 Hpt#5
828-906 aa · 79 aa · 8.6% of protein
Raw token
Hpt:828:2.26e-16:906:79:84- Raw architecture: HAMP:182:0.00000000000133:247:66:69#HisKA:293:1.12e-19:357:65:64#HATPase_c:404:7.48e-34:519:116:109#Response_reg:670:3.65e-36:781:112:111#Hpt:828:2.26e-16:906:79:84
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c,1 Response_reg,1 Hpt
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000006925::NC_004337.2::G00024
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span2874042-2876798Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000006925::NC_004337.2::G00024Context members
SF2799
Partner locus tags
SF2799
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for NP_708580.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSF2799Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_004337.2Sequence record reported by the local genomic context database.
Genomic interval2 874 042-2 876 798 nt2 757 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 874 042-2 876 798 ntGCF_000006925::NC_004337.2::G00024
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000006925::NC_004337.2::G00024Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004337.2All displayed genes belong to this local TCS context.
Neighborhood span2 874 042-2 876 798 nt2 757 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 874 042 nt2 876 798 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
SF2799GCF_000006925#SF2799
HKUnorthodoxCurrent focus
2 874 042-2 876 798 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architecturesCache_4 + HAMP + HisKA + HATPase_c + Response_reg + Hpt6 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0372532
Simplified PFAM architecture for HKOC_0372532
PFAM domain coverage: 572 / 918 aa (62.3%)
1 aa918 aa
sCache_4HAMPHisKAHATPase_cResponse_regHpt
- Simplified architecture: sCache_4 + HAMP + HisKA + HATPase_c + Response_reg + Hpt
- Raw architecture: sCache_4[31-177] | HAMP[198-248] | HisKA[293-357] | HATPase_c[404-518] | Response_reg[670-780] | Hpt[828-910]
- Domain count: 6
- Matched identifier: HKOC_0372532
- Positioned domains: sCache_4 31-177 ; HAMP 198-248 ; HisKA 293-357 ; HATPase_c 404-518 ; Response_reg 670-780 ; Hpt 828-910
Cluster members and taxonomy
Representative gene: GCF_000006925#SF2799
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 198 214 · GCF_000006925
AssemblyASM692v2 · Complete Genomereference genome · haploid
Genome composition4 828 820 bp · 50,5% GCShigella flexneri 2a str. 301
Signal transduction countsGenes 54 · HK 25 · RR 29CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusShigella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Shigella
Related genes
Preview from the same derived genome key