1 HAMP#1
196-264 aa · 69 aa · 13.9% of protein
Raw token
HAMP:196:0.000000881:264:69:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SF2603
Histidine kinase, Classic
Shigella flexneri 2a str. 301 · GCF_000006925
ClassHKTypeClassicLength496 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000006925#SF2603Stable P2CS identifier used across views.
GenomeGCF_000006925Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length496 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage245 / 496 aa (49.4%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa496 aa
Domain-by-domain annotation3 items
2 HisKA#2
270-337 aa · 68 aa · 13.7% of protein
Raw token
HisKA:270:0.0000000000000606:337:68:643 HATPase_c#3
383-490 aa · 108 aa · 21.8% of protein
Raw token
HATPase_c:383:1.15e-23:490:108:109- Raw architecture: HAMP:196:0.000000881:264:69:69#HisKA:270:0.0000000000000606:337:68:64#HATPase_c:383:1.15e-23:490:108:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000006925::NC_004337.2::G00023
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span2674541-2676031Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000006925::NC_004337.2::G00023Context members
SF2603
Partner locus tags
SF2603
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqNP_708393.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H2VYL3Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H2VYL3_SHIFLDisplay identifier provided by UniProt.
GO / PubMed6 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSF2603Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_004337.2Sequence record reported by the local genomic context database.
Genomic interval2 674 541-2 676 031 nt1 491 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 674 541-2 676 031 ntGCF_000006925::NC_004337.2::G00023
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000006925::NC_004337.2::G00023Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004337.2All displayed genes belong to this local TCS context.
Neighborhood span2 674 541-2 676 031 nt1 491 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 674 541 nt2 676 031 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
SF2603GCF_000006925#SF2603
HKClassicCurrent focus
2 674 541-2 676 031 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1498700
Simplified PFAM architecture for HKOC_1498700
PFAM domain coverage: 176 / 496 aa (35.5%)
1 aa496 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[271-337] | HATPase_c[383-491]
- Domain count: 2
- Matched identifier: HKOC_1498700
- Positioned domains: HisKA 271-337 ; HATPase_c 383-491
Cluster members and taxonomy
Representative gene: GCF_000006925#SF2603
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 198 214 · GCF_000006925
AssemblyASM692v2 · Complete Genomereference genome · haploid
Genome composition4 828 820 bp · 50,5% GCShigella flexneri 2a str. 301
Signal transduction countsGenes 54 · HK 25 · RR 29CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusShigella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Shigella
Related genes
Preview from the same derived genome key