1 His_kinase#1
370-448 aa · 79 aa · 14.1% of protein
Raw token
His_kinase:370:4.87e-33:448:80:80P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SF2198
Histidine kinase, Classic
Shigella flexneri 2a str. 301 · GCF_000006925
ClassHKTypeClassicLength561 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000006925#SF2198Stable P2CS identifier used across views.
GenomeGCF_000006925Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Domain signature
Compact overview inferred from the domain field
His_kinaseHATPase_c
Protein length561 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage168 / 561 aa (29.9%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa561 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
468-556 aa · 89 aa · 15.9% of protein
Raw token
HATPase_c:468:0.00000000463:556:105:109- Raw architecture: His_kinase:370:4.87e-33:448:80:80#HATPase_c:468:0.00000000463:556:105:109
- Domain description: 1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000006925::NC_004337.2::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2223232-2225633Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000006925::NC_004337.2::G00016Context members
SF2197SF2198
Partner locus tags
SF2197SF2198
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for NP_708017.2.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSF2198Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_004337.2Sequence record reported by the local genomic context database.
Genomic interval2 223 948-2 225 633 nt1 686 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 223 232-2 225 633 ntGCF_000006925::NC_004337.2::G00016
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000006925::NC_004337.2::G00016Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004337.2All displayed genes belong to this local TCS context.
Neighborhood span2 223 232-2 225 633 nt2 402 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 223 232 nt2 225 633 nt
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architecture5TM-5TMR_LYT + GAF_2 + His_kinase3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1253754
Simplified PFAM architecture for HKOC_1253754
PFAM domain coverage: 360 / 561 aa (64.2%)
1 aa561 aa
5TM-5TMR_LYTGAF_2His_kinase
- Simplified architecture: 5TM-5TMR_LYT + GAF_2 + His_kinase
- Raw architecture: 5TM-5TMR_LYT[27-196] | GAF_2[241-352] | His_kinase[371-448]
- Domain count: 3
- Matched identifier: HKOC_1253754
- Positioned domains: 5TM-5TMR_LYT 27-196 ; GAF_2 241-352 ; His_kinase 371-448
Cluster members and taxonomy
Representative gene: GCF_000005845#b2126
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 198 214 · GCF_000006925
AssemblyASM692v2 · Complete Genomereference genome · haploid
Genome composition4 828 820 bp · 50,5% GCShigella flexneri 2a str. 301
Signal transduction countsGenes 54 · HK 25 · RR 29CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusShigella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Shigella
Related genes
Preview from the same derived genome key