1 Hpt#1
7-93 aa · 87 aa · 13.3% of protein
Raw token
Hpt:7:0.00000000000000148:93:87:84P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SF1937
Histidine kinase, CheA
Shigella flexneri 2a str. 301 · GCF_000006925
ClassHKTypeCheALength654 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000006925#SF1937Stable P2CS identifier used across views.
GenomeGCF_000006925Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Domain signature
Compact overview inferred from the domain field
HptH-kinase_dimHATPase_cCheW
Protein length654 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage415 / 654 aa (63.5%)Merged over positioned domains only.
Domain description1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa654 aa
Domain-by-domain annotation4 items
2 H-kinase_dim#2
263-324 aa · 62 aa · 9.5% of protein
Raw token
H-kinase_dim:263:1.57e-18:324:66:673 HATPase_c#3
371-508 aa · 138 aa · 21.1% of protein
Raw token
HATPase_c:371:9.67e-17:508:138:1094 CheW#4
513-640 aa · 128 aa · 19.6% of protein
Raw token
CheW:513:9.07e-30:640:134:138- Raw architecture: Hpt:7:0.00000000000000148:93:87:84#H-kinase_dim:263:1.57e-18:324:66:67#HATPase_c:371:9.67e-17:508:138:109#CheW:513:9.07e-30:640:134:138
- Domain description: 1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheW
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000006925::NC_004337.2::G00012
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1971988-1973952Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000006925::NC_004337.2::G00012Context members
SF1937
Partner locus tags
SF1937
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for NP_707783.2.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSF1937Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_004337.2Sequence record reported by the local genomic context database.
Genomic interval1 971 988-1 973 952 nt1 965 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 971 988-1 973 952 ntGCF_000006925::NC_004337.2::G00012
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000006925::NC_004337.2::G00012Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004337.2All displayed genes belong to this local TCS context.
Neighborhood span1 971 988-1 973 952 nt1 965 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 971 988 nt1 973 952 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
SF1937GCF_000006925#SF1937
HKCheACurrent focus
1 971 988-1 973 952 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architectureHpt + CheY-binding + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0886032
Simplified PFAM architecture for HKOC_0886032
PFAM domain coverage: 484 / 654 aa (74.0%)
1 aa654 aa
HptCheY-bindingH-kinase_dimHATPase_cCheW
- Simplified architecture: Hpt + CheY-binding + H-kinase_dim + HATPase_c + CheW
- Raw architecture: Hpt[8-100] | CheY-binding[161-223] | H-kinase_dim[261-324] | HATPase_c[372-508] | CheW[514-640]
- Domain count: 5
- Matched identifier: HKOC_0886032
- Positioned domains: Hpt 8-100 ; CheY-binding 161-223 ; H-kinase_dim 261-324 ; HATPase_c 372-508 ; CheW 514-640
Cluster members and taxonomy
Representative gene: GCF_000006925#SF1937
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 198 214 · GCF_000006925
AssemblyASM692v2 · Complete Genomereference genome · haploid
Genome composition4 828 820 bp · 50,5% GCShigella flexneri 2a str. 301
Signal transduction countsGenes 54 · HK 25 · RR 29CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusShigella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Shigella
Related genes
Preview from the same derived genome key