1 HAMP#1
140-207 aa · 68 aa · 15.7% of protein
Raw token
HAMP:140:0.0000000813:207:72:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
Z_RS12325
Histidine kinase, Classic
Escherichia coli O157:H7 str. EDL933 · GCF_000006665
ClassHKTypeClassicLength433 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000006665#Z_RS12325Stable P2CS identifier used across views.
GenomeGCF_000006665Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length433 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage235 / 433 aa (54.3%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa433 aa
Domain-by-domain annotation3 items
2 HisKA#2
211-269 aa · 59 aa · 13.6% of protein
Raw token
HisKA:211:0.000000000363:269:62:643 HATPase_c#3
316-423 aa · 108 aa · 24.9% of protein
Raw token
HATPase_c:316:1.62e-29:423:109:109- Raw architecture: HAMP:140:0.0000000813:207:72:69#HisKA:211:0.000000000363:269:62:64#HATPase_c:316:1.62e-29:423:109:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000006665::NC_002655.2::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2357246-2359270Genomic interval covered by the local TCS group.
Identifiers
Old locus tagZ2610RefSeq proteinWP_000732491.1
Context group ID
GCF_000006665::NC_002655.2::G00012Context members
Z_RS12320Z_RS12325
Partner locus tags
Z_RS12320Z_RS12325
Partner old locus tags
Z2609Z2610
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000732491.1Primary protein accession used for annex mappings.
UniProt accessionA0AAV3H7X8Primary UniProt accession resolved in the annex database.
UniProt IDA0AAV3H7X8_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagZ_RS12325Primary locus identifier stored in the genes table.
Old locus tagZ2610Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_002655.2Sequence record reported by the local genomic context database.
Genomic interval2 357 969-2 359 270 nt1 302 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 357 246-2 359 270 ntGCF_000006665::NC_002655.2::G00012
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000006665::NC_002655.2::G00012Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_002655.2All displayed genes belong to this local TCS context.
Neighborhood span2 357 246-2 359 270 nt2 025 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 357 246 nt2 359 270 nt
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000006665#Z_RS12325The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2140052
Simplified PFAM architecture for HKOC_2140052
PFAM domain coverage: 209 / 433 aa (48.3%)
1 aa433 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[163-206] | HisKA[212-270] | HATPase_c[318-423]
- Domain count: 3
- Matched identifier: HKOC_2140052
- Positioned domains: HAMP 163-206 ; HisKA 212-270 ; HATPase_c 318-423
Cluster members and taxonomy
Representative gene: GCF_000006665#Z_RS12325
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 155 864 · GCF_000006665
AssemblyASM666v1 · Chromosomehaploid
Genome composition5 620 522 bp · 50,5% GCEscherichia coli O157:H7 str. EDL933
Signal transduction countsGenes 64 · HK 31 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key