1 PBPb#1
41-255 aa · 215 aa · 17.3% of protein
Raw token
PBPb:41:1.77e-38:255:223:219P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
Y_RS12295
Histidine kinase, Hybrid
Yersinia pestis KIM10+ · GCF_000006645
ClassHKTypeHybridLength1242 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000006645#Y_RS12295Stable P2CS identifier used across views.
GenomeGCF_000006645Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Yersiniaceae; Yersinia
Domain signature
Compact overview inferred from the domain field
PBPbSBP_bac_3HisKAHATPase_cResponse_reg
Protein length1242 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage722 / 1242 aa (58.1%)Merged over positioned domains only.
Domain description1 PBPb,1 SBP_bac_3,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa1242 aa
Domain-by-domain annotation5 items
2 SBP_bac_3#2
290-502 aa · 213 aa · 17.1% of protein
Raw token
SBP_bac_3:290:2.57e-32:502:220:2243 HisKA#3
693-756 aa · 64 aa · 5.2% of protein
Raw token
HisKA:693:0.0000000000000105:756:64:644 HATPase_c#4
803-919 aa · 117 aa · 9.4% of protein
Raw token
HATPase_c:803:2.65e-29:919:117:1095 Response_reg#5
947-1059 aa · 113 aa · 9.1% of protein
Raw token
Response_reg:947:3.39e-26:1059:113:111- Raw architecture: PBPb:41:1.77e-38:255:223:219#SBP_bac_3:290:2.57e-32:502:220:224#HisKA:693:0.0000000000000105:756:64:64#HATPase_c:803:2.65e-29:919:117:109#Response_reg:947:3.39e-26:1059:113:111
- Domain description: 1 PBPb,1 SBP_bac_3,1 HisKA,1 HATPase_c,1 Response_reg
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000006645::NC_004088.1::G00022
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2634154-2638612Genomic interval covered by the local TCS group.
Identifiers
Old locus tagy2387RefSeq proteinWP_002220434.1
Context group ID
GCF_000006645::NC_004088.1::G00022Context members
Y_RS12290Y_RS12295
Partner locus tags
Y_RS12290Y_RS12295
Partner old locus tags
y2386y2387
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002220434.1Primary protein accession used for annex mappings.
UniProt accessionA0A873VPJ8Primary UniProt accession resolved in the annex database.
UniProt IDA0A873VPJ8_YERPEDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagY_RS12295Primary locus identifier stored in the genes table.
Old locus tagy2387Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_004088.1Sequence record reported by the local genomic context database.
Genomic interval2 634 884-2 638 612 nt3 729 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 634 154-2 638 612 ntGCF_000006645::NC_004088.1::G00022
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000006645::NC_004088.1::G00022Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004088.1All displayed genes belong to this local TCS context.
Neighborhood span2 634 154-2 638 612 nt4 459 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 634 154 nt2 638 612 nt
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000006645#Y_RS12295The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0137442
Simplified PFAM architecture for HKOC_0137442
PFAM domain coverage: 291 / 1242 aa (23.4%)
1 aa1242 aa
HisKAHATPase_cResponse_reg
- Simplified architecture: HisKA + HATPase_c + Response_reg
- Raw architecture: HisKA[693-756] | HATPase_c[804-918] | Response_reg[947-1058]
- Domain count: 3
- Matched identifier: HKOC_0137442
- Positioned domains: HisKA 693-756 ; HATPase_c 804-918 ; Response_reg 947-1058
Cluster members and taxonomy
Representative gene: GCF_000006645#Y_RS12295
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 187 410 · GCF_000006645
AssemblyASM664v1 · Complete Genomehaploid
Genome composition4 701 745 bp · 47,5% GCYersinia pestis KIM10+
Signal transduction countsGenes 50 · HK 23 · RR 27CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyYersiniaceaeGenusYersinia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Yersiniaceae7Yersinia
Related genes
Preview from the same derived genome key