Gene detail

Y_RS06650

Histidine kinase, Classic

Yersinia pestis KIM10+ · GCF_000006645

ClassHKTypeClassicLength908 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000006645#Y_RS06650Stable P2CS identifier used across views.
GenomeGCF_000006645Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Yersiniaceae; Yersinia
Selected clusterHKOC_0393745Run 6 · 673 sequences · id 100% · cov 80% · representative
External referencesWP_002209649.1 · A0A0H2YHT4 · MIST4 Y_RS06650RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

KdpDGAF_3HisKAHATPase_c
Protein length908 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage505 / 908 aa (55.6%)Merged over positioned domains only.
Domain description1 KdpD,1 GAF_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa908 aa
KdpD: 23-231 aa (209 aa)1GAF_3: 528-646 aa (119 aa)2HisKA: 666-732 aa (67 aa)3HATPase_c: 777-886 aa (110 aa)4
Domain-by-domain annotation4 items
1 KdpD#1
23-231 aa · 209 aa · 23.0% of protein
Raw tokenKdpD:23:7.9e-144:231:209:210
2 GAF_3#2
528-646 aa · 119 aa · 13.1% of protein
Raw tokenGAF_3:528:0.0000000000000743:646:130:129
3 HisKA#3
666-732 aa · 67 aa · 7.4% of protein
Raw tokenHisKA:666:0.00000000000151:732:67:64
4 HATPase_c#4
777-886 aa · 110 aa · 12.1% of protein
Raw tokenHATPase_c:777:1.72e-28:886:110:109
  • Raw architecture: KdpD:23:7.9e-144:231:209:210#GAF_3:528:0.0000000000000743:646:130:129#HisKA:666:0.00000000000151:732:67:64#HATPase_c:777:1.72e-28:886:110:109
  • Domain description: 1 KdpD,1 GAF_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000006645::NC_004088.1::G00008
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1407563-1411211Genomic interval covered by the local TCS group.
Identifiers
Context group IDGCF_000006645::NC_004088.1::G00008
Context members
Y_RS06645Y_RS06650
Partner locus tags
Y_RS06645Y_RS06650
Partner old locus tags
y1261y1262
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002209649.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H2YHT4Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H2YHT4_YERPNDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagY_RS06650Primary locus identifier stored in the genes table.
Old locus tagy1262Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_004088.1Sequence record reported by the local genomic context database.
Genomic interval1 408 485-1 411 211 nt2 727 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 407 563-1 411 211 ntGCF_000006645::NC_004088.1::G00008

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000006645::NC_004088.1::G00008

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004088.1All displayed genes belong to this local TCS context.
Neighborhood span1 407 563-1 411 211 nt3 649 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 407 563 nt1 411 211 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

Y_RS06645GCF_000006645#Y_RS06645
RROmpR

1 407 563-1 408 249 nt · Reverse (-)

Old locus y1261RefSeq WP_029562574.1
Y_RS06650GCF_000006645#Y_RS06650
HKClassicCurrent focus

1 408 485-1 411 211 nt · Reverse (-)

Old locus y1262RefSeq WP_002209649.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0393745Run 6 · HK · 673 sequences
Representative sequenceGCF_000006645#Y_RS06650The current gene is the representative for this cluster.
PFAM architectureKdpD + DUF4118 + GAF_3 + HisKA + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0393745

Simplified PFAM architecture for HKOC_0393745

PFAM domain coverage: 609 / 908 aa (67.1%)

1 aa908 aa
KdpD: 23-231 aaKdpDDUF4118: 404-509 aaDUF4118GAF_3: 529-646 aaGAF_3HisKA: 666-732 aaHisKAHATPase_c: 777-885 aaHATPase_c
KdpDDUF4118GAF_3HisKAHATPase_c
  • Simplified architecture: KdpD + DUF4118 + GAF_3 + HisKA + HATPase_c
  • Raw architecture: KdpD[23-231] | DUF4118[404-509] | GAF_3[529-646] | HisKA[666-732] | HATPase_c[777-885]
  • Domain count: 5
  • Matched identifier: HKOC_0393745
  • Positioned domains: KdpD 23-231 ; DUF4118 404-509 ; GAF_3 529-646 ; HisKA 666-732 ; HATPase_c 777-885
Cluster members and taxonomy
Visualization

Representative gene: GCF_000006645#Y_RS06650

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 187 410 · GCF_000006645
AssemblyASM664v1 · Complete Genomehaploid
Genome composition4 701 745 bp · 47,5% GCYersinia pestis KIM10+
Signal transduction countsGenes 50 · HK 23 · RR 27CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyYersiniaceaeGenusYersinia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Yersiniaceae7Yersinia

Related genes

Preview from the same derived genome key