1 CpxA_peri#1
81-162 aa · 82 aa · 17.9% of protein
Raw token
CpxA_peri:81:0.0000000000463:162:85:134P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
Y_RS00345
Histidine kinase, Classic
Yersinia pestis KIM10+ · GCF_000006645
ClassHKTypeClassicLength458 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000006645#Y_RS00345Stable P2CS identifier used across views.
GenomeGCF_000006645Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Yersiniaceae; Yersinia
Domain signature
Compact overview inferred from the domain field
CpxA_periHAMPHisKAHATPase_c
Protein length458 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage322 / 458 aa (70.3%)Merged over positioned domains only.
Domain description1 CpxA_peri,1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa458 aa
Domain-by-domain annotation4 items
2 HAMP#2
165-232 aa · 68 aa · 14.8% of protein
Raw token
HAMP:165:0.00000000000352:232:68:693 HisKA#3
238-299 aa · 62 aa · 13.5% of protein
Raw token
HisKA:238:3.02e-16:299:63:644 HATPase_c#4
346-455 aa · 110 aa · 24.0% of protein
Raw token
HATPase_c:346:4.55e-27:455:111:109- Raw architecture: CpxA_peri:81:0.0000000000463:162:85:134#HAMP:165:0.00000000000352:232:68:69#HisKA:238:3.02e-16:299:63:64#HATPase_c:346:4.55e-27:455:111:109
- Domain description: 1 CpxA_peri,1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000006645::NC_004088.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span77072-79143Genomic interval covered by the local TCS group.
Identifiers
Old locus tagy0069RefSeq proteinWP_002208971.1
Context group ID
GCF_000006645::NC_004088.1::G00001Context members
Y_RS00340Y_RS00345
Partner locus tags
Y_RS00340Y_RS00345
Partner old locus tags
y0067y0069
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002208971.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H2YNN7Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H2YNN7_YERPNDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagY_RS00345Primary locus identifier stored in the genes table.
Old locus tagy0069Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_004088.1Sequence record reported by the local genomic context database.
Genomic interval77 767-79 143 nt1 377 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span77 072-79 143 ntGCF_000006645::NC_004088.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000006645::NC_004088.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_004088.1All displayed genes belong to this local TCS context.
Neighborhood span77 072-79 143 nt2 072 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
77 072 nt79 143 nt
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000006645#Y_RS00345The current gene is the representative for this cluster.
PFAM architectureCpxA_peri + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1858249
Simplified PFAM architecture for HKOC_1858249
PFAM domain coverage: 300 / 458 aa (65.5%)
1 aa458 aa
CpxA_periHAMPHisKAHATPase_c
- Simplified architecture: CpxA_peri + HAMP + HisKA + HATPase_c
- Raw architecture: CpxA_peri[82-159] | HAMP[181-232] | HisKA[238-299] | HATPase_c[347-454]
- Domain count: 4
- Matched identifier: HKOC_1858249
- Positioned domains: CpxA_peri 82-159 ; HAMP 181-232 ; HisKA 238-299 ; HATPase_c 347-454
Cluster members and taxonomy
Representative gene: GCF_000006645#Y_RS00345
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 187 410 · GCF_000006645
AssemblyASM664v1 · Complete Genomehaploid
Genome composition4 701 745 bp · 47,5% GCYersinia pestis KIM10+
Signal transduction countsGenes 50 · HK 23 · RR 27CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyYersiniaceaeGenusYersinia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Yersiniaceae7Yersinia
Related genes
Preview from the same derived genome key