1 His_kinase#1
370-448 aa · 79 aa · 14.1% of protein
Raw token
His_kinase:370:4.87e-33:448:80:80P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
b2126
Histidine kinase, Classic
Escherichia coli str. K-12 substr. MG1655 · GCF_000005845
ClassHKTypeClassicLength561 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000005845#b2126Stable P2CS identifier used across views.
GenomeGCF_000005845Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
His_kinaseHATPase_c
Protein length561 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage168 / 561 aa (29.9%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
468-556 aa · 89 aa · 15.9% of protein
Raw token
HATPase_c:468:0.00000000463:556:105:109- Raw architecture: His_kinase:370:4.87e-33:448:80:80#HATPase_c:468:0.00000000463:556:105:109
- Domain description: 1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000005845::NC_000913.3::G00017
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2212243-2214644Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000005845::NC_000913.3::G00017Context members
b2125b2126
Partner locus tags
b2125b2126
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for NP_416630.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagb2126Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_000913.3Sequence record reported by the local genomic context database.
Genomic interval2 212 959-2 214 644 nt1 686 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 212 243-2 214 644 ntGCF_000005845::NC_000913.3::G00017
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000005845::NC_000913.3::G00017Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_000913.3All displayed genes belong to this local TCS context.
Neighborhood span2 212 243-2 214 644 nt2 402 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 212 243 nt2 214 644 nt
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architecture5TM-5TMR_LYT + GAF_2 + His_kinase3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1253754
Simplified PFAM architecture for HKOC_1253754
PFAM domain coverage: 360 / 561 aa (64.2%)
1 aa561 aa
5TM-5TMR_LYTGAF_2His_kinase
- Simplified architecture: 5TM-5TMR_LYT + GAF_2 + His_kinase
- Raw architecture: 5TM-5TMR_LYT[27-196] | GAF_2[241-352] | His_kinase[371-448]
- Domain count: 3
- Matched identifier: HKOC_1253754
- Positioned domains: 5TM-5TMR_LYT 27-196 ; GAF_2 241-352 ; His_kinase 371-448
Cluster members and taxonomy
Representative gene: GCF_000005845#b2126
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 511 145 · GCF_000005845
AssemblyASM584v2 · Complete Genomereference genome · haploid
Genome composition4 641 652 bp · 51,0% GCEscherichia coli str. K-12 substr. MG1655
Signal transduction countsGenes 63 · HK 31 · RR 32CheA 2 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key