1 HAMP#1
304-372 aa · 69 aa · 11.7% of protein
Raw token
HAMP:304:0.0000000000772:372:69:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ACFY6D_RS02015
Histidine kinase, Classic
Mediterraneibacter gnavus · GCF_964272225
ClassHKTypeClassicLength590 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_964272225#ACFY6D_RS02015Stable P2CS identifier used across views.
GenomeGCF_964272225Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length590 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage242 / 590 aa (41.0%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa590 aa
Domain-by-domain annotation3 items
2 His_kinase#2
387-466 aa · 80 aa · 13.6% of protein
Raw token
His_kinase:387:3.14e-31:466:80:803 HATPase_c#3
485-577 aa · 93 aa · 15.8% of protein
Raw token
HATPase_c:485:0.000000000000222:577:108:109- Raw architecture: HAMP:304:0.0000000000772:372:69:69#His_kinase:387:3.14e-31:466:80:80#HATPase_c:485:0.000000000000222:577:108:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_964272225::NZ_OZ186746.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span429593-432416Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_964272225::NZ_OZ186746.1::G00006Context members
ACFY6D_RS02015ACFY6D_RS02020
Partner locus tags
ACFY6D_RS02015ACFY6D_RS02020
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_173865083.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagACFY6D_RS02015Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_OZ186746.1Sequence record reported by the local genomic context database.
Genomic interval429 593-431 365 nt1 773 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span429 593-432 416 ntGCF_964272225::NZ_OZ186746.1::G00006
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_964272225::NZ_OZ186746.1::G00006Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_OZ186746.1All displayed genes belong to this local TCS context.
Neighborhood span429 593-432 416 nt2 824 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
429 593 nt432 416 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ACFY6D_RS02015GCF_964272225#ACFY6D_RS02015
HKClassicCurrent focus
429 593-431 365 nt · Forward (+)
ACFY6D_RS02020GCF_964272225#ACFY6D_RS02020
RRunclassified
431 343-432 416 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_003471005#DW270_RS15340Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1111247
Simplified PFAM architecture for HKOC_1111247
PFAM domain coverage: 174 / 590 aa (29.5%)
1 aa590 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[387-466] | HATPase_c[484-577]
- Domain count: 2
- Matched identifier: HKOC_1111247
- Positioned domains: His_kinase 387-466 ; HATPase_c 484-577
Cluster members and taxonomy
Representative gene: GCF_003471005#DW270_RS15340
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 33 038 · GCF_964272225
AssemblyLUMC_Rgna_QRD023 · Complete Genomehaploid
Genome composition3 562 076 bp · 42,5% GCMediterraneibacter gnavus
Signal transduction countsGenes 81 · HK 39 · RR 41CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter
Related genes
Preview from the same derived genome key