1 dCache_1#1
42-221 aa · 180 aa · 31.5% of protein
Raw token
dCache_1:42:0.00000292:221:181:195P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ACFY5M_RS01135
Histidine kinase, Classic
Mediterraneibacter gnavus · GCF_964271945
ClassHKTypeClassicLength571 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_964271945#ACFY5M_RS01135Stable P2CS identifier used across views.
GenomeGCF_964271945Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Domain signature
Compact overview inferred from the domain field
dCache_1HAMPHis_kinaseHATPase_c
Protein length571 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage430 / 571 aa (75.3%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa571 aa
Domain-by-domain annotation4 items
2 HAMP#2
281-347 aa · 67 aa · 11.7% of protein
Raw token
HAMP:281:0.00000000000966:347:67:693 His_kinase#3
362-441 aa · 80 aa · 14.0% of protein
Raw token
His_kinase:362:1.84e-28:441:80:804 HATPase_c#4
458-560 aa · 103 aa · 18.0% of protein
Raw token
HATPase_c:458:0.00000000000014:560:112:109- Raw architecture: dCache_1:42:0.00000292:221:181:195#HAMP:281:0.00000000000966:347:67:69#His_kinase:362:1.84e-28:441:80:80#HATPase_c:458:0.00000000000014:560:112:109
- Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_964271945::NZ_OZ186708.1::G00005
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span250137-251852Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_964271945::NZ_OZ186708.1::G00005Context members
ACFY5M_RS01135
Partner locus tags
ACFY5M_RS01135
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_101872311.1Primary protein accession used for annex mappings.
UniProt accessionA0A2N5Q0R5Primary UniProt accession resolved in the annex database.
UniProt IDA0A2N5Q0R5_MEDGNDisplay identifier provided by UniProt.
GO / PubMed2 / 2Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagACFY5M_RS01135Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_OZ186708.1Sequence record reported by the local genomic context database.
Genomic interval250 137-251 852 nt1 716 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span250 137-251 852 ntGCF_964271945::NZ_OZ186708.1::G00005
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_964271945::NZ_OZ186708.1::G00005Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_OZ186708.1All displayed genes belong to this local TCS context.
Neighborhood span250 137-251 852 nt1 716 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
250 137 nt251 852 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
ACFY5M_RS01135GCF_964271945#ACFY5M_RS01135
HKClassicCurrent focus
250 137-251 852 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_002865285#CDL20_RS06690Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1208206
Simplified PFAM architecture for HKOC_1208206
PFAM domain coverage: 230 / 571 aa (40.3%)
1 aa571 aa
HAMPHis_kinaseHATPase_c
- Simplified architecture: HAMP + His_kinase + HATPase_c
- Raw architecture: HAMP[295-346] | His_kinase[363-439] | HATPase_c[459-559]
- Domain count: 3
- Matched identifier: HKOC_1208206
- Positioned domains: HAMP 295-346 ; His_kinase 363-439 ; HATPase_c 459-559
Cluster members and taxonomy
Representative gene: GCF_002865285#CDL20_RS06690
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 33 038 · GCF_964271945
AssemblyLUMC_Rgna_QRD039 · Complete Genomehaploid
Genome composition3 511 739 bp · 43,0% GCMediterraneibacter gnavus
Signal transduction countsGenes 83 · HK 39 · RR 43CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter
Related genes
Preview from the same derived genome key