1 HAMP#1
289-358 aa · 70 aa · 11.8% of protein
Raw token
HAMP:289:0.000000000774:358:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ACFY5W_RS04215
Histidine kinase, Classic
Mediterraneibacter gnavus · GCF_964271915
ClassHKTypeClassicLength591 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_964271915#ACFY5W_RS04215Stable P2CS identifier used across views.
GenomeGCF_964271915Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length591 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 591 aa (42.5%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa591 aa
Domain-by-domain annotation3 items
2 His_kinase#2
380-459 aa · 80 aa · 13.5% of protein
Raw token
His_kinase:380:5.75e-29:459:80:803 HATPase_c#3
485-585 aa · 101 aa · 17.1% of protein
Raw token
HATPase_c:485:0.000000784:585:101:109- Raw architecture: HAMP:289:0.000000000774:358:70:69#His_kinase:380:5.75e-29:459:80:80#HATPase_c:485:0.000000784:585:101:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_964271915::NZ_OZ186706.1::G00014
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span850821-854223Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_964271915::NZ_OZ186706.1::G00014Context members
ACFY5W_RS04215ACFY5W_RS04220
Partner locus tags
ACFY5W_RS04215ACFY5W_RS04220
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_117636835.1Primary protein accession used for annex mappings.
UniProt accessionA0A396GC77Primary UniProt accession resolved in the annex database.
UniProt IDA0A396GC77_MEDGNDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagACFY5W_RS04215Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_OZ186706.1Sequence record reported by the local genomic context database.
Genomic interval850 821-852 596 nt1 776 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span850 821-854 223 ntGCF_964271915::NZ_OZ186706.1::G00014
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_964271915::NZ_OZ186706.1::G00014Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_OZ186706.1All displayed genes belong to this local TCS context.
Neighborhood span850 821-854 223 nt3 403 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
850 821 nt854 223 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ACFY5W_RS04215GCF_964271915#ACFY5W_RS04215
HKClassicCurrent focus
850 821-852 596 nt · Forward (+)
ACFY5W_RS04220GCF_964271915#ACFY5W_RS04220
RRunclassified
852 601-854 223 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_003436535#DXD36_RS15675Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase1 domain in the representative PFAM annotation.
PFAM architecture for HKOC_1106394
Simplified PFAM architecture for HKOC_1106394
PFAM domain coverage: 80 / 591 aa (13.5%)
1 aa591 aa
His_kinase
- Simplified architecture: His_kinase
- Raw architecture: His_kinase[380-459]
- Domain count: 1
- Matched identifier: HKOC_1106394
- Positioned domains: His_kinase 380-459
Cluster members and taxonomy
Representative gene: GCF_003436535#DXD36_RS15675
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 33 038 · GCF_964271915
AssemblyLUMC_Rgna_QRD028 · Complete Genomehaploid
Genome composition3 315 330 bp · 42,5% GCMediterraneibacter gnavus
Signal transduction countsGenes 85 · HK 41 · RR 43CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter
Related genes
Preview from the same derived genome key