1 HAMP#1
154-227 aa · 74 aa · 16.2% of protein
Raw token
HAMP:154:0.00000000000000329:227:74:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ACFY5W_RS02375
Histidine kinase, Classic
Mediterraneibacter gnavus · GCF_964271915
ClassHKTypeClassicLength457 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_964271915#ACFY5W_RS02375Stable P2CS identifier used across views.
GenomeGCF_964271915Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length457 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage250 / 457 aa (54.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa457 aa
Domain-by-domain annotation3 items
2 HisKA#2
233-297 aa · 65 aa · 14.2% of protein
Raw token
HisKA:233:0.0000000000000259:297:65:643 HATPase_c#3
343-453 aa · 111 aa · 24.3% of protein
Raw token
HATPase_c:343:4.45e-28:453:111:109- Raw architecture: HAMP:154:0.00000000000000329:227:74:69#HisKA:233:0.0000000000000259:297:65:64#HATPase_c:343:4.45e-28:453:111:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_964271915::NZ_OZ186706.1::G00008
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span479733-481777Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_964271915::NZ_OZ186706.1::G00008Context members
ACFY5W_RS02370ACFY5W_RS02375
Partner locus tags
ACFY5W_RS02370ACFY5W_RS02375
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_064786281.1Primary protein accession used for annex mappings.
UniProt accessionA0A3E4UV14Primary UniProt accession resolved in the annex database.
UniProt IDA0A3E4UV14_MEDGNDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagACFY5W_RS02375Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_OZ186706.1Sequence record reported by the local genomic context database.
Genomic interval480 404-481 777 nt1 374 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span479 733-481 777 ntGCF_964271915::NZ_OZ186706.1::G00008
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_964271915::NZ_OZ186706.1::G00008Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_OZ186706.1All displayed genes belong to this local TCS context.
Neighborhood span479 733-481 777 nt2 045 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
479 733 nt481 777 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ACFY5W_RS02370GCF_964271915#ACFY5W_RS02370
RROmpR
479 733-480 407 nt · Forward (+)
ACFY5W_RS02375GCF_964271915#ACFY5W_RS02375
HKClassicCurrent focus
480 404-481 777 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_020537205#LIP96_RS06805Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1880883
Simplified PFAM architecture for HKOC_1880883
PFAM domain coverage: 235 / 457 aa (51.4%)
1 aa457 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[171-227] | HisKA[232-297] | HATPase_c[343-454]
- Domain count: 3
- Matched identifier: HKOC_1880883
- Positioned domains: HAMP 171-227 ; HisKA 232-297 ; HATPase_c 343-454
Cluster members and taxonomy
Representative gene: GCF_020537205#LIP96_RS06805
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 33 038 · GCF_964271915
AssemblyLUMC_Rgna_QRD028 · Complete Genomehaploid
Genome composition3 315 330 bp · 42,5% GCMediterraneibacter gnavus
Signal transduction countsGenes 85 · HK 41 · RR 43CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter
Related genes
Preview from the same derived genome key