1 HAMP#1
305-374 aa · 70 aa · 11.6% of protein
Raw token
HAMP:305:0.000000000818:374:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ACFY5R_RS00750
Histidine kinase, Classic
Mediterraneibacter gnavus · GCF_964271885
ClassHKTypeClassicLength601 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_964271885#ACFY5R_RS00750Stable P2CS identifier used across views.
GenomeGCF_964271885Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length601 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage206 / 601 aa (34.3%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation3 items
2 His_kinase#2
390-469 aa · 80 aa · 13.3% of protein
Raw token
His_kinase:390:1.31e-21:469:80:803 HATPase_c#3
488-543 aa · 56 aa · 9.3% of protein
Raw token
HATPase_c:488:0.00000247:543:56:109- Raw architecture: HAMP:305:0.000000000818:374:70:69#His_kinase:390:1.31e-21:469:80:80#HATPase_c:488:0.00000247:543:56:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_964271885::NZ_OZ186418.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span154360-157688Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_964271885::NZ_OZ186418.1::G00001Context members
ACFY5R_RS00750ACFY5R_RS00755
Partner locus tags
ACFY5R_RS00750ACFY5R_RS00755
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_118053783.1Primary protein accession used for annex mappings.
UniProt accessionA0A414P4N8Primary UniProt accession resolved in the annex database.
UniProt IDA0A414P4N8_MEDGNDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagACFY5R_RS00750Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_OZ186418.1Sequence record reported by the local genomic context database.
Genomic interval154 360-156 165 nt1 806 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span154 360-157 688 ntGCF_964271885::NZ_OZ186418.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_964271885::NZ_OZ186418.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_OZ186418.1All displayed genes belong to this local TCS context.
Neighborhood span154 360-157 688 nt3 329 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
154 360 nt157 688 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ACFY5R_RS00750GCF_964271885#ACFY5R_RS00750
HKClassicCurrent focus
154 360-156 165 nt · Forward (+)
ACFY5R_RS00755GCF_964271885#ACFY5R_RS00755
RRunclassified
156 162-157 688 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_024459975#NE704_RS12945Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase1 domain in the representative PFAM annotation.
PFAM architecture for HKOC_1050324
Simplified PFAM architecture for HKOC_1050324
PFAM domain coverage: 80 / 601 aa (13.3%)
1 aa601 aa
His_kinase
- Simplified architecture: His_kinase
- Raw architecture: His_kinase[390-469]
- Domain count: 1
- Matched identifier: HKOC_1050324
- Positioned domains: His_kinase 390-469
Cluster members and taxonomy
Representative gene: GCF_024459975#NE704_RS12945
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 33 038 · GCF_964271885
AssemblyLUMC_Rgna_QRD001 · Complete Genomehaploid
Genome composition3 096 184 bp · 43,0% GCMediterraneibacter gnavus
Signal transduction countsGenes 78 · HK 38 · RR 39CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter
Related genes
Preview from the same derived genome key