Gene detail

E1245_RS08490

Response regulator OmpR family

Clostridioides difficile · GCF_900692275

ClassRRTypeOmpRLength230 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900692275#E1245_RS08490Stable P2CS identifier used across views.
GenomeGCF_900692275Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterRROC_1200142Run 7 · 310 sequences · id 100% · cov 80%
External referencesWP_003422314.1 · D5Q9X1 · MIST4 E1245_RS08490RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regTrans_reg_C
Protein length230 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage187 / 230 aa (81.3%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa230 aa
Response_reg: 5-114 aa (110 aa)1Trans_reg_C: 152-228 aa (77 aa)2
Domain-by-domain annotation2 items
1 Response_reg#1
5-114 aa · 110 aa · 47.8% of protein
Raw tokenResponse_reg:5:7.78e-38:114:111:111
2 Trans_reg_C#2
152-228 aa · 77 aa · 33.5% of protein
Raw tokenTrans_reg_C:152:7.99e-32:228:77:77
  • Raw architecture: Response_reg:5:7.78e-38:114:111:111#Trans_reg_C:152:7.99e-32:228:77:77
  • Domain description: 1 Response_reg,1 Trans_reg_C
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900692275::NZ_CAADEJ010000008.1::G00031
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span51187-53050Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA1710368_01712RefSeq proteinWP_003422314.1
Context group IDGCF_900692275::NZ_CAADEJ010000008.1::G00031
Context members
E1245_RS08485E1245_RS08490
Partner locus tags
E1245_RS08485E1245_RS08490
Partner old locus tags
SAMEA1710368_01711SAMEA1710368_01712
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003422314.1Primary protein accession used for annex mappings.
UniProt accessionD5Q9X1Primary UniProt accession resolved in the annex database.
UniProt IDD5Q9X1_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE1245_RS08490Primary locus identifier stored in the genes table.
Old locus tagSAMEA1710368_01712Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAADEJ010000008.1Sequence record reported by the local genomic context database.
Genomic interval52 358-53 050 nt693 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span51 187-53 050 ntGCF_900692275::NZ_CAADEJ010000008.1::G00031

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900692275::NZ_CAADEJ010000008.1::G00031

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAADEJ010000008.1All displayed genes belong to this local TCS context.
Neighborhood span51 187-53 050 nt1 864 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
51 187 nt53 050 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E1245_RS08485GCF_900692275#E1245_RS08485
HKClassic

51 187-52 368 nt · Reverse (-)

Old locus SAMEA1710368_01711RefSeq WP_003422313.1
E1245_RS08490GCF_900692275#E1245_RS08490
RROmpRCurrent focus

52 358-53 050 nt · Reverse (-)

Old locus SAMEA1710368_01712RefSeq WP_003422314.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_1200142Run 7 · RR · 310 sequences
Representative sequenceGCF_000155065#QAE_RS0217720Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.

PFAM architecture for RROC_1200142

Simplified PFAM architecture for RROC_1200142

PFAM domain coverage: 185 / 230 aa (80.4%)

1 aa230 aa
Response_reg: 5-113 aaResponse_regResponse_reg: 5-113 aaResponse_regTrans_reg_C: 152-227 aaTrans_reg_CTrans_reg_C: 152-227 aaTrans_reg_C
Response_regTrans_reg_C
  • Simplified architecture: Response_reg + Trans_reg_C
  • Raw architecture: Response_reg[5-113] | Trans_reg_C[152-227]
  • Domain count: 2
  • Matched identifier: RROC_1200142
  • Positioned domains: Response_reg 5-113 ; Response_reg 5-113 ; Trans_reg_C 152-227 ; Trans_reg_C 152-227
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0217720

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900692275
Assembly9221_6#35 · Contighaploid
Genome composition3 969 496 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key