Gene detail

E1245_RS04445

Response regulator NarL family

Clostridioides difficile · GCF_900692275

ClassRRTypeNarLLength215 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900692275#E1245_RS04445Stable P2CS identifier used across views.
GenomeGCF_900692275Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterRROC_1906741Run 7 · 303 sequences · id 100% · cov 80%
External referencesWP_009905386.1 · A0AAX3GVP8 · MIST4 E1245_RS04445RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regHTH_LUXR
Protein length215 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage168 / 215 aa (78.1%)Merged over positioned domains only.
Domain description1 Response_reg,1 HTH_LUXRSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa215 aa
Response_reg: 6-118 aa (113 aa)1HTH_LUXR: 153-207 aa (55 aa)2
Domain-by-domain annotation2 items
1 Response_reg#1
6-118 aa · 113 aa · 52.6% of protein
Raw tokenResponse_reg:6:1.77e-28:118:113:111
2 HTH_LUXR#2
153-207 aa · 55 aa · 25.6% of protein
Raw tokenHTH_LUXR:153:7.67e-21:207:55:58
  • Raw architecture: Response_reg:6:1.77e-28:118:113:111#HTH_LUXR:153:7.67e-21:207:55:58
  • Domain description: 1 Response_reg,1 HTH_LUXR
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900692275::NZ_CAADEJ010000003.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span215902-217705Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA1710368_00904RefSeq proteinWP_009905386.1
Context group IDGCF_900692275::NZ_CAADEJ010000003.1::G00013
Context members
E1245_RS04445E1245_RS04450
Partner locus tags
E1245_RS04445E1245_RS04450
Partner old locus tags
SAMEA1710368_00904SAMEA1710368_00905
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009905386.1Primary protein accession used for annex mappings.
UniProt accessionA0AAX3GVP8Primary UniProt accession resolved in the annex database.
UniProt IDA0AAX3GVP8_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE1245_RS04445Primary locus identifier stored in the genes table.
Old locus tagSAMEA1710368_00904Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAADEJ010000003.1Sequence record reported by the local genomic context database.
Genomic interval215 902-216 549 nt648 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span215 902-217 705 ntGCF_900692275::NZ_CAADEJ010000003.1::G00013

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900692275::NZ_CAADEJ010000003.1::G00013

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAADEJ010000003.1All displayed genes belong to this local TCS context.
Neighborhood span215 902-217 705 nt1 804 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
215 902 nt217 705 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E1245_RS04445GCF_900692275#E1245_RS04445
RRNarLCurrent focus

215 902-216 549 nt · Reverse (-)

Old locus SAMEA1710368_00904RefSeq WP_009905386.1
E1245_RS04450GCF_900692275#E1245_RS04450
HKClassic

216 542-217 705 nt · Reverse (-)

Old locus SAMEA1710368_00905RefSeq WP_003424698.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_1906741Run 7 · RR · 303 sequences
Representative sequenceGCF_000155065#QAE_RS0206210Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + GerE2 domains in the representative PFAM annotation.

PFAM architecture for RROC_1906741

Simplified PFAM architecture for RROC_1906741

PFAM domain coverage: 168 / 215 aa (78.1%)

1 aa215 aa
Response_reg: 6-117 aaResponse_regResponse_reg: 6-117 aaResponse_regGerE: 152-207 aaGerEGerE: 152-207 aaGerE
Response_regGerE
  • Simplified architecture: Response_reg + GerE
  • Raw architecture: Response_reg[6-117] | GerE[152-207]
  • Domain count: 2
  • Matched identifier: RROC_1906741
  • Positioned domains: Response_reg 6-117 ; Response_reg 6-117 ; GerE 152-207 ; GerE 152-207
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0206210

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900692275
Assembly9221_6#35 · Contighaploid
Genome composition3 969 496 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key