1 HisKA#1
558-624 aa · 67 aa · 8.6% of protein
Raw token
HisKA:558:1.65e-18:624:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E1252_RS04310
Histidine kinase, Classic
Clostridioides difficile · GCF_900691975
ClassHKTypeClassicLength778 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900691975#E1252_RS04310Stable P2CS identifier used across views.
GenomeGCF_900691975Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length778 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage172 / 778 aa (22.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa778 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
671-775 aa · 105 aa · 13.5% of protein
Raw token
HATPase_c:671:0.000000000398:775:110:109- Raw architecture: HisKA:558:1.65e-18:624:67:64#HATPase_c:671:0.000000000398:775:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_900691975::NZ_CAADDR010000001.1::G00015
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span921625-924649Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA1710759_00857RefSeq proteinWP_225541028.1
Context group ID
GCF_900691975::NZ_CAADDR010000001.1::G00015Context members
E1252_RS04310E1252_RS04315
Partner locus tags
E1252_RS04310E1252_RS04315
Partner old locus tags
SAMEA1710759_00857SAMEA1710759_00858
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_225541028.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE1252_RS04310Primary locus identifier stored in the genes table.
Old locus tagSAMEA1710759_00857Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAADDR010000001.1Sequence record reported by the local genomic context database.
Genomic interval921 625-923 961 nt2 337 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span921 625-924 649 ntGCF_900691975::NZ_CAADDR010000001.1::G00015
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_900691975::NZ_CAADDR010000001.1::G00015Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAADDR010000001.1All displayed genes belong to this local TCS context.
Neighborhood span921 625-924 649 nt3 025 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
921 625 nt924 649 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E1252_RS04310GCF_900691975#E1252_RS04310
HKClassicCurrent focus
921 625-923 961 nt · Reverse (-)
E1252_RS04315GCF_900691975#E1252_RS04315
RROmpR
923 933-924 649 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000448905#QAY_RS12650Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0599072
Simplified PFAM architecture for HKOC_0599072
PFAM domain coverage: 172 / 778 aa (22.1%)
1 aa778 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[558-624] | HATPase_c[671-775]
- Domain count: 2
- Matched identifier: HKOC_0599072
- Positioned domains: HisKA 558-624 ; HATPase_c 671-775
Cluster members and taxonomy
Representative gene: GCF_000448905#QAY_RS12650
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_900691975
Assembly9221_1#35 · Contighaploid
Genome composition4 031 609 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key