Gene detail

E1109_RS00515

Histidine kinase, Classic

Clostridioides difficile · GCF_900687785

ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_900687785#E1109_RS00515Stable P2CS identifier used across views.
GenomeGCF_900687785Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1748568Run 6 · 18 sequences · id 100% · cov 80%
External referencesWP_022618021.1 · MIST4 E1109_RS00515RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage176 / 467 aa (37.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa467 aa
HisKA: 245-313 aa (69 aa)1HATPase_c: 360-466 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
245-313 aa · 69 aa · 14.8% of protein
Raw tokenHisKA:245:0.000000000000406:313:69:64
2 HATPase_c#2
360-466 aa · 107 aa · 22.9% of protein
Raw tokenHATPase_c:360:1.73e-27:466:108:109
  • Raw architecture: HisKA:245:0.000000000000406:313:69:64#HATPase_c:360:1.73e-27:466:108:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_900687785::NZ_CAADAB010000001.1::G00003
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span100168-101571Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA1402347_00097RefSeq proteinWP_022618021.1
Context group IDGCF_900687785::NZ_CAADAB010000001.1::G00003
Context members
E1109_RS00515
Partner locus tags
E1109_RS00515
Partner old locus tags
SAMEA1402347_00097
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_022618021.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE1109_RS00515Primary locus identifier stored in the genes table.
Old locus tagSAMEA1402347_00097Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAADAB010000001.1Sequence record reported by the local genomic context database.
Genomic interval100 168-101 571 nt1 404 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span100 168-101 571 ntGCF_900687785::NZ_CAADAB010000001.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900687785::NZ_CAADAB010000001.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAADAB010000001.1All displayed genes belong to this local TCS context.
Neighborhood span100 168-101 571 nt1 404 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
100 168 nt101 571 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

E1109_RS00515GCF_900687785#E1109_RS00515
HKClassicCurrent focus

100 168-101 571 nt · Reverse (-)

Old locus SAMEA1402347_00097RefSeq WP_022618021.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1748568Run 6 · HK · 18 sequences
Representative sequenceGCF_000531715#BN191_RS10615Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1748568

Simplified PFAM architecture for HKOC_1748568

PFAM domain coverage: 167 / 467 aa (35.8%)

1 aa467 aa
HisKA: 245-306 aaHisKAHATPase_c: 362-466 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-306] | HATPase_c[362-466]
  • Domain count: 2
  • Matched identifier: HKOC_1748568
  • Positioned domains: HisKA 245-306 ; HATPase_c 362-466
Cluster members and taxonomy
Visualization

Representative gene: GCF_000531715#BN191_RS10615

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900687785
Assembly7614_4#76 · Contighaploid
Genome composition4 302 892 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 48 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key