1 HisKA#1
196-260 aa · 65 aa · 15.3% of protein
Raw token
HisKA:196:0.0000000000161:260:65:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E1112_RS00850
Histidine kinase, Classic
Clostridioides difficile · GCF_900687725
ClassHKTypeClassicLength425 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900687725#E1112_RS00850Stable P2CS identifier used across views.
GenomeGCF_900687725Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length425 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage183 / 425 aa (43.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
307-424 aa · 118 aa · 27.8% of protein
Raw token
HATPase_c:307:1.45e-18:424:119:109- Raw architecture: HisKA:196:0.0000000000161:260:65:64#HATPase_c:307:1.45e-18:424:119:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_900687725::NZ_CAACZY010000001.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span190902-192831Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA1402390_00172RefSeq proteinWP_003434036.1
Context group ID
GCF_900687725::NZ_CAACZY010000001.1::G00001Context members
E1112_RS00845E1112_RS00850
Partner locus tags
E1112_RS00845E1112_RS00850
Partner old locus tags
SAMEA1402390_00171SAMEA1402390_00172
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003434036.1Primary protein accession used for annex mappings.
UniProt accessionQ185Q2Primary UniProt accession resolved in the annex database.
UniProt IDQ185Q2_CLOD6Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE1112_RS00850Primary locus identifier stored in the genes table.
Old locus tagSAMEA1402390_00172Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAACZY010000001.1Sequence record reported by the local genomic context database.
Genomic interval191 554-192 831 nt1 278 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span190 902-192 831 ntGCF_900687725::NZ_CAACZY010000001.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_900687725::NZ_CAACZY010000001.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAACZY010000001.1All displayed genes belong to this local TCS context.
Neighborhood span190 902-192 831 nt1 930 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
190 902 nt192 831 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E1112_RS00845GCF_900687725#E1112_RS00845
RROmpR
190 902-191 570 nt · Forward (+)
E1112_RS00850GCF_900687725#E1112_RS00850
HKClassicCurrent focus
191 554-192 831 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009205#CD630_RS11460Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2215987
Simplified PFAM architecture for HKOC_2215987
PFAM domain coverage: 179 / 425 aa (42.1%)
1 aa425 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[197-260] | HATPase_c[308-422]
- Domain count: 2
- Matched identifier: HKOC_2215987
- Positioned domains: HisKA 197-260 ; HATPase_c 308-422
Cluster members and taxonomy
Representative gene: GCF_000009205#CD630_RS11460
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_900687725
Assembly7614_4#70 · Contighaploid
Genome composition4 218 281 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key