Gene detail

E1122_RS14520

Histidine kinase, Classic

Clostridioides difficile · GCF_900687715

ClassHKTypeClassicLength542 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900687715#E1122_RS14520Stable P2CS identifier used across views.
GenomeGCF_900687715Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1317370Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_236879437.1 · MIST4 E1122_RS14520RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

SBP_bac_3HisKAHATPase_c
Protein length542 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage321 / 542 aa (59.2%)Merged over positioned domains only.
Domain description1 SBP_bac_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa542 aa
SBP_bac_3: 1-156 aa (156 aa)1HisKA: 324-386 aa (63 aa)2HATPase_c: 435-536 aa (102 aa)3
Domain-by-domain annotation3 items
1 SBP_bac_3#1
1-156 aa · 156 aa · 28.8% of protein
Raw tokenSBP_bac_3:1:4.33e-33:156:160:224
2 HisKA#2
324-386 aa · 63 aa · 11.6% of protein
Raw tokenHisKA:324:0.0000000000000563:386:63:64
3 HATPase_c#3
435-536 aa · 102 aa · 18.8% of protein
Raw tokenHATPase_c:435:3.34e-23:536:103:109
  • Raw architecture: SBP_bac_3:1:4.33e-33:156:160:224#HisKA:324:0.0000000000000563:386:63:64#HATPase_c:435:3.34e-23:536:103:109
  • Domain description: 1 SBP_bac_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900687715::NZ_CAACZZ010000010.1::G00044
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span86577-89527Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA1402386_02912RefSeq proteinWP_236879437.1
Context group IDGCF_900687715::NZ_CAACZZ010000010.1::G00044
Context members
E1122_RS14520E1122_RS14525
Partner locus tags
E1122_RS14520E1122_RS14525
Partner old locus tags
SAMEA1402386_02912SAMEA1402386_02913
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_236879437.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE1122_RS14520Primary locus identifier stored in the genes table.
Old locus tagSAMEA1402386_02912Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAACZZ010000010.1Sequence record reported by the local genomic context database.
Genomic interval86 577-88 205 nt1 629 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span86 577-89 527 ntGCF_900687715::NZ_CAACZZ010000010.1::G00044

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900687715::NZ_CAACZZ010000010.1::G00044

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAACZZ010000010.1All displayed genes belong to this local TCS context.
Neighborhood span86 577-89 527 nt2 951 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
86 577 nt89 527 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E1122_RS14520GCF_900687715#E1122_RS14520
HKClassicCurrent focus

86 577-88 205 nt · Forward (+)

Old locus SAMEA1402386_02912RefSeq WP_236879437.1
E1122_RS14525GCF_900687715#E1122_RS14525
RRNtrC

88 205-89 527 nt · Forward (+)

Old locus SAMEA1402386_02913RefSeq WP_009893260.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1317370Run 6 · HK · 1 sequences
Representative sequenceGCF_900687715#E1122_RS14520The current gene is the representative for this cluster.
PFAM architectureSBP_bac_3 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1317370

Simplified PFAM architecture for HKOC_1317370

PFAM domain coverage: 321 / 542 aa (59.2%)

1 aa542 aa
SBP_bac_3: 2-155 aaSBP_bac_3HisKA: 326-387 aaHisKAHATPase_c: 433-537 aaHATPase_c
SBP_bac_3HisKAHATPase_c
  • Simplified architecture: SBP_bac_3 + HisKA + HATPase_c
  • Raw architecture: SBP_bac_3[2-155] | HisKA[326-387] | HATPase_c[433-537]
  • Domain count: 3
  • Matched identifier: HKOC_1317370
  • Positioned domains: SBP_bac_3 2-155 ; HisKA 326-387 ; HATPase_c 433-537
Cluster members and taxonomy
Visualization

Representative gene: GCF_900687715#E1122_RS14520

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900687715
Assembly7614_4#74 · Scaffoldhaploid
Genome composition4 206 072 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 48 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key