Gene detail

E1110_RS15615

Histidine kinase, Classic

Clostridioides difficile · GCF_900687655

ClassHKTypeClassicLength386 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900687655#E1110_RS15615Stable P2CS identifier used across views.
GenomeGCF_900687655Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2557912Run 6 · 33 sequences · id 100% · cov 80%
External referencesWP_021360162.1 · MIST4 E1110_RS15615RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length386 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 386 aa (59.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for E1110_RS15615
Domain-by-domain annotation3 items
1 HAMP#1
84-152 aa · 69 aa · 17.9% of protein
Raw tokenHAMP:84:0.000000655:152:70:69
2 HisKA#2
164-217 aa · 54 aa · 14.0% of protein
Raw tokenHisKA:164:0.0000000474:217:54:64
3 HATPase_c#3
278-382 aa · 105 aa · 27.2% of protein
Raw tokenHATPase_c:278:2.19e-19:382:106:109
  • Raw architecture: HAMP:84:0.000000655:152:70:69#HisKA:164:0.0000000474:217:54:64#HATPase_c:278:2.19e-19:382:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900687655::NZ_CAACZW010000014.1::G00042
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span12187-14009Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA1402416_03137RefSeq proteinWP_021360162.1
Context group IDGCF_900687655::NZ_CAACZW010000014.1::G00042
Context members
E1110_RS15610E1110_RS15615
Partner locus tags
E1110_RS15610E1110_RS15615
Partner old locus tags
SAMEA1402416_03136SAMEA1402416_03137
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021360162.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE1110_RS15615Primary locus identifier stored in the genes table.
Old locus tagSAMEA1402416_03137Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAACZW010000014.1Sequence record reported by the local genomic context database.
Genomic interval12 849-14 009 nt1 161 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span12 187-14 009 ntGCF_900687655::NZ_CAACZW010000014.1::G00042

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900687655::NZ_CAACZW010000014.1::G00042

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAACZW010000014.1All displayed genes belong to this local TCS context.
Neighborhood span12 187-14 009 nt1 823 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
12 187 nt14 009 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E1110_RS15610GCF_900687655#E1110_RS15610
RROmpR

12 187-12 861 nt · Forward (+)

Old locus SAMEA1402416_03136RefSeq WP_021360163.1
E1110_RS15615GCF_900687655#E1110_RS15615
HKClassicCurrent focus

12 849-14 009 nt · Forward (+)

Old locus SAMEA1402416_03137RefSeq WP_021360162.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2557912Run 6 · HK · 33 sequences
Representative sequenceGCF_000448845#QAQ_RS02295Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2557912

Simplified PFAM architecture for HKOC_2557912

PFAM domain coverage: 219 / 386 aa (56.7%)

1 aa386 aa
HAMP: 106-151 aaHAMPHisKA: 164-231 aaHisKAHATPase_c: 278-382 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[106-151] | HisKA[164-231] | HATPase_c[278-382]
  • Domain count: 3
  • Matched identifier: HKOC_2557912
  • Positioned domains: HAMP 106-151 ; HisKA 164-231 ; HATPase_c 278-382
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448845#QAQ_RS02295

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 33 over 33 total members. Page 1 / 1.

GCF_000448845#QAQ_RS02295 (representative)
QAQ_RS02295 · HK · Classic
RefSeq: WP_021360162.1
GCF_000448865#QAS_RS02365
QAS_RS02365 · HK · Classic
RefSeq: WP_021360162.1
GCF_000450965#QQQ_RS02460
QQQ_RS02460 · HK · Classic
RefSeq: WP_021360162.1
GCF_000451605#QQU_RS02185
QQU_RS02185 · HK · Classic
RefSeq: WP_021360162.1
GCF_000451925#QU9_RS02160
QU9_RS02160 · HK · Classic
RefSeq: WP_021360162.1
GCF_000452085#QUU_RS02375
QUU_RS02375 · HK · Classic
RefSeq: WP_021360162.1
GCF_000452145#QW1_RS15695
QW1_RS15695 · HK · Classic
RefSeq: WP_021360162.1
GCF_000452185#QW5_RS02250
QW5_RS02250 · HK · Classic
RefSeq: WP_021360162.1
GCF_000473625#QU1_RS02690
QU1_RS02690 · HK · Classic
RefSeq: WP_021360162.1
GCF_002301835#BGU47_RS15715
BGU47_RS15715 · HK · Classic
RefSeq: WP_021360162.1
GCF_002303655#BGU72_RS11055
BGU72_RS11055 · HK · Classic
RefSeq: WP_021360162.1
GCF_002303675#BGU73_RS08035
BGU73_RS08035 · HK · Classic
RefSeq: WP_021360162.1
GCF_003863005#EGL84_RS17315
EGL84_RS17315 · HK · Classic
RefSeq: WP_021360162.1
GCF_004314725#E0O54_RS07760
E0O54_RS07760 · HK · Classic
RefSeq: WP_021360162.1
GCF_004314825#E0O57_RS08830
E0O57_RS08830 · HK · Classic
RefSeq: WP_021360162.1
GCF_007002415#EWL76_RS12050
EWL76_RS12050 · HK · Classic
RefSeq: WP_021360162.1
GCF_008245165#FQN08_RS02665
FQN08_RS02665 · HK · Classic
RefSeq: WP_021360162.1
GCF_011602815#HAX81_RS16785
HAX81_RS16785 · HK · Classic
RefSeq: WP_021360162.1
GCF_012641505#HG230_RS13295
HG230_RS13295 · HK · Classic
RefSeq: WP_021360162.1
GCF_015351935#ITJ29_RS02630
ITJ29_RS02630 · HK · Classic
RefSeq: WP_021360162.1
GCF_015352195#ITJ13_RS05380
ITJ13_RS05380 · HK · Classic
RefSeq: WP_021360162.1
GCF_018885105#KNZ76_RS02635
KNZ76_RS02635 · HK · Classic
RefSeq: WP_021360162.1
GCF_020295225#HO256_RS08920
HO256_RS08920 · HK · Classic
RefSeq: WP_021360162.1
GCF_030250935#QQO50_RS03595
QQO50_RS03595 · HK · Classic
RefSeq: WP_021360162.1
GCF_030251285#QQO37_RS05415
QQO37_RS05415 · HK · Classic
RefSeq: WP_021360162.1
GCF_030251985#QQO66_RS17810
QQO66_RS17810 · HK · Classic
RefSeq: WP_021360162.1
GCF_038753285#ABCQ30_RS14555
ABCQ30_RS14555 · HK · Classic
RefSeq: WP_021360162.1
GCF_900010935#A4Y63_RS07385
A4Y63_RS07385 · HK · Classic
RefSeq: WP_021360162.1
GCF_900013115#A4Y25_RS07470
A4Y25_RS07470 · HK · Classic
RefSeq: WP_021360162.1
GCF_900165885#B2A91_RS16940
B2A91_RS16940 · HK · Classic
RefSeq: WP_021360162.1
GCF_900165895#B2C07_RS11185
B2C07_RS11185 · HK · Classic
RefSeq: WP_021360162.1
GCF_900165905#B2C15_RS16690
B2C15_RS16690 · HK · Classic
RefSeq: WP_021360162.1
GCF_900687655#E1110_RS15615
E1110_RS15615 · HK · Classic
RefSeq: WP_021360162.1

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900687655
Assembly7614_4#63 · Contighaploid
Genome composition4 146 704 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 95 · HK 46 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key