1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw token
HisKA:449:0.00000000369:514:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E1104_RS06725
Histidine kinase, Classic
Clostridioides difficile · GCF_900687575
ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContexttriad
Gene IDGCF_900687575#E1104_RS06725Stable P2CS identifier used across views.
GenomeGCF_900687575Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa671 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw token
HATPase_c:565:1.12e-29:668:104:109- Raw architecture: HisKA:449:0.00000000369:514:66:64#HATPase_c:565:1.12e-29:668:104:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labeltriadGCF_900687575::NZ_CAADAD010000004.1::G00021
Group size33 locus tags listed below.
HK / RR1 / 2Counts resolved for the local TCS neighborhood.
Context span152277-155771Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA1402341_01344RefSeq proteinWP_032544350.1
Context group ID
GCF_900687575::NZ_CAADAD010000004.1::G00021Context members
E1104_RS06720E1104_RS06725E1104_RS06730
Partner locus tags
E1104_RS06720E1104_RS06725E1104_RS06730
Partner old locus tags
SAMEA1402341_01343SAMEA1402341_01344SAMEA1402341_01345
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_032544350.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE1104_RS06725Primary locus identifier stored in the genes table.
Old locus tagSAMEA1402341_01344Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAADAD010000004.1Sequence record reported by the local genomic context database.
Genomic interval153 007-155 022 nt2 016 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span152 277-155 771 ntGCF_900687575::NZ_CAADAD010000004.1::G00021
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_900687575::NZ_CAADAD010000004.1::G00021Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labeltriadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAADAD010000004.1All displayed genes belong to this local TCS context.
Neighborhood span152 277-155 771 nt3 495 nt
Members31 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
152 277 nt155 771 nt
Neighborhood gene cards
3 genes in the current local neighborhood.
E1104_RS06720GCF_900687575#E1104_RS06720
RROmpR
152 277-152 957 nt · Reverse (-)
E1104_RS06725GCF_900687575#E1104_RS06725
HKClassicCurrent focus
153 007-155 022 nt · Reverse (-)
E1104_RS06730GCF_900687575#E1104_RS06730
RROmpR
155 094-155 771 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000450445#QKY_RS16220Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0842604
Simplified PFAM architecture for HKOC_0842604
PFAM domain coverage: 170 / 671 aa (25.3%)
1 aa671 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[450-514] | HATPase_c[563-667]
- Domain count: 2
- Matched identifier: HKOC_0842604
- Positioned domains: HisKA 450-514 ; HATPase_c 563-667
Cluster members and taxonomy
Representative gene: GCF_000450445#QKY_RS16220
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_900687575
Assembly7614_4#57 · Scaffoldhaploid
Genome composition4 025 312 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key