Gene detail

E4V63_RS15085

Histidine kinase, Classic

Clostridioides difficile · GCF_900687405

ClassHKTypeClassicLength413 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900687405#E4V63_RS15085Stable P2CS identifier used across views.
GenomeGCF_900687405Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2328362Run 6 · 12 sequences · id 100% · cov 80%
External referencesWP_021396672.1 · MIST4 E4V63_RS15085RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length413 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 413 aa (40.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for E4V63_RS15085
Domain-by-domain annotation2 items
1 HisKA#1
195-255 aa · 61 aa · 14.8% of protein
Raw tokenHisKA:195:0.00000000000087:255:61:64
2 HATPase_c#2
302-407 aa · 106 aa · 25.7% of protein
Raw tokenHATPase_c:302:1.43e-26:407:107:109
  • Raw architecture: HisKA:195:0.00000000000087:255:61:64#HATPase_c:302:1.43e-26:407:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900687405::NZ_CAACZO010000017.1::G00042
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span36751-38686Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA1022486_03052RefSeq proteinWP_021396672.1
Context group IDGCF_900687405::NZ_CAACZO010000017.1::G00042
Context members
E4V63_RS15085E4V63_RS15090
Partner locus tags
E4V63_RS15085E4V63_RS15090
Partner old locus tags
SAMEA1022486_03052SAMEA1022486_03053
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021396672.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE4V63_RS15085Primary locus identifier stored in the genes table.
Old locus tagSAMEA1022486_03052Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAACZO010000017.1Sequence record reported by the local genomic context database.
Genomic interval36 751-37 992 nt1 242 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span36 751-38 686 ntGCF_900687405::NZ_CAACZO010000017.1::G00042

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900687405::NZ_CAACZO010000017.1::G00042

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAACZO010000017.1All displayed genes belong to this local TCS context.
Neighborhood span36 751-38 686 nt1 936 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
36 751 nt38 686 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E4V63_RS15085GCF_900687405#E4V63_RS15085
HKClassicCurrent focus

36 751-37 992 nt · Reverse (-)

Old locus SAMEA1022486_03052RefSeq WP_021396672.1
E4V63_RS15090GCF_900687405#E4V63_RS15090
RROmpR

38 003-38 686 nt · Reverse (-)

Old locus SAMEA1022486_03053RefSeq WP_003418728.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2328362Run 6 · HK · 12 sequences
Representative sequenceGCF_000450145#QK3_RS05495Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2328362

Simplified PFAM architecture for HKOC_2328362

PFAM domain coverage: 172 / 413 aa (41.6%)

1 aa413 aa
HisKA: 193-255 aaHisKAHATPase_c: 302-410 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[193-255] | HATPase_c[302-410]
  • Domain count: 2
  • Matched identifier: HKOC_2328362
  • Positioned domains: HisKA 193-255 ; HATPase_c 302-410
Cluster members and taxonomy
Visualization

Representative gene: GCF_000450145#QK3_RS05495

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900687405
Assembly6437_4#10 · Scaffoldhaploid
Genome composition4 057 710 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 94 · HK 45 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key