1 HisKA#1
82-144 aa · 63 aa · 20.9% of protein
Raw token
HisKA:82:0.0000000745:144:63:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E4V63_RS03310
Histidine kinase, Classic
Clostridioides difficile · GCF_900687405
ClassHKTypeClassicLength302 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900687405#E4V63_RS03310Stable P2CS identifier used across views.
GenomeGCF_900687405Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length302 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage163 / 302 aa (54.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
196-295 aa · 100 aa · 33.1% of protein
Raw token
HATPase_c:196:2.16e-22:295:100:109- Raw architecture: HisKA:82:0.0000000745:144:63:64#HATPase_c:196:2.16e-22:295:100:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_900687405::NZ_CAACZO010000002.1::G00007
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span188621-190202Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA1022486_00678RefSeq proteinWP_021408245.1
Context group ID
GCF_900687405::NZ_CAACZO010000002.1::G00007Context members
E4V63_RS03305E4V63_RS03310
Partner locus tags
E4V63_RS03305E4V63_RS03310
Partner old locus tags
SAMEA1022486_00677SAMEA1022486_00678
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021408245.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE4V63_RS03310Primary locus identifier stored in the genes table.
Old locus tagSAMEA1022486_00678Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAACZO010000002.1Sequence record reported by the local genomic context database.
Genomic interval189 294-190 202 nt909 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span188 621-190 202 ntGCF_900687405::NZ_CAACZO010000002.1::G00007
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_900687405::NZ_CAACZO010000002.1::G00007Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAACZO010000002.1All displayed genes belong to this local TCS context.
Neighborhood span188 621-190 202 nt1 582 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
188 621 nt190 202 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E4V63_RS03305GCF_900687405#E4V63_RS03305
RROmpR
188 621-189 292 nt · Forward (+)
E4V63_RS03310GCF_900687405#E4V63_RS03310
HKClassicCurrent focus
189 294-190 202 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000450785#QO7_RS09735Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2884719
Simplified PFAM architecture for HKOC_2884719
PFAM domain coverage: 165 / 302 aa (54.6%)
1 aa302 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[82-144] | HATPase_c[195-296]
- Domain count: 2
- Matched identifier: HKOC_2884719
- Positioned domains: HisKA 82-144 ; HATPase_c 195-296
Cluster members and taxonomy
Representative gene: GCF_000450785#QO7_RS09735
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_900687405
Assembly6437_4#10 · Scaffoldhaploid
Genome composition4 057 710 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 94 · HK 45 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key