1 HAMP#1
94-171 aa · 78 aa · 19.2% of protein
Raw token
HAMP:94:0.00000000705:171:78:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E1P11_RS18345
Histidine kinase, Classic
Clostridioides difficile · GCF_900684305
ClassHKTypeClassicLength407 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900684305#E1P11_RS18345Stable P2CS identifier used across views.
GenomeGCF_900684305Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length407 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 407 aa (61.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa407 aa
Domain-by-domain annotation3 items
2 HisKA#2
183-248 aa · 66 aa · 16.2% of protein
Raw token
HisKA:183:0.00000000128:248:66:643 HATPase_c#3
298-404 aa · 107 aa · 26.3% of protein
Raw token
HATPase_c:298:1.56e-26:404:107:109- Raw architecture: HAMP:94:0.00000000705:171:78:69#HisKA:183:0.00000000128:248:66:64#HATPase_c:298:1.56e-26:404:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_900684305::NZ_CAACZA010000027.1::G00059
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span18325-20460Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA840512_03656RefSeq proteinWP_330360524.1
Context group ID
GCF_900684305::NZ_CAACZA010000027.1::G00059Context members
E1P11_RS18345E1P11_RS18350
Partner locus tags
E1P11_RS18345E1P11_RS18350
Partner old locus tags
SAMEA840512_03656SAMEA840512_03657
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_330360524.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE1P11_RS18345Primary locus identifier stored in the genes table.
Old locus tagSAMEA840512_03656Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAACZA010000027.1Sequence record reported by the local genomic context database.
Genomic interval18 325-19 548 nt1 224 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span18 325-20 460 ntGCF_900684305::NZ_CAACZA010000027.1::G00059
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_900684305::NZ_CAACZA010000027.1::G00059Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAACZA010000027.1All displayed genes belong to this local TCS context.
Neighborhood span18 325-20 460 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
18 325 nt20 460 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E1P11_RS18345GCF_900684305#E1P11_RS18345
HKClassicCurrent focus
18 325-19 548 nt · Reverse (-)
E1P11_RS18350GCF_900684305#E1P11_RS18350
RROmpR
19 768-20 460 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000027105#CDR20291_RS02605Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2379999
Simplified PFAM architecture for HKOC_2379999
PFAM domain coverage: 223 / 407 aa (54.8%)
1 aa407 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[121-171] | HisKA[184-248] | HATPase_c[298-404]
- Domain count: 3
- Matched identifier: HKOC_2379999
- Positioned domains: HAMP 121-171 ; HisKA 184-248 ; HATPase_c 298-404
Cluster members and taxonomy
Representative gene: GCF_000027105#CDR20291_RS02605
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_900684305
Assembly4995_2#8 · Scaffoldhaploid
Genome composition4 124 263 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key