Gene detail

DBQ24_RS00540

Histidine kinase, Classic

Clostridioides difficile · GCF_900243205

ClassHKTypeClassicLength386 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900243205#DBQ24_RS00540Stable P2CS identifier used across views.
GenomeGCF_900243205Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2557601Run 6 · 352 sequences · id 100% · cov 80%
External referencesWP_009889050.1 · A0AB74QZK6 · MIST4 DBQ24_RS00540RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length386 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage149 / 386 aa (38.6%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for DBQ24_RS00540
Domain-by-domain annotation2 items
1 HisKA_3#1
187-250 aa · 64 aa · 16.6% of protein
Raw tokenHisKA_3:187:9.36e-20:250:65:68
2 HATPase_c#2
293-377 aa · 85 aa · 22.0% of protein
Raw tokenHATPase_c:293:0.00000000000129:377:104:109
  • Raw architecture: HisKA_3:187:9.36e-20:250:65:68#HATPase_c:293:0.00000000000129:377:104:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900243205::NZ_OEZU01000007.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span71530-73327Genomic interval covered by the local TCS group.
Context group IDGCF_900243205::NZ_OEZU01000007.1::G00012
Context members
DBQ24_RS00540DBQ24_RS00545
Partner locus tags
DBQ24_RS00540DBQ24_RS00545
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009889050.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74QZK6Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74QZK6_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDBQ24_RS00540Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_OEZU01000007.1Sequence record reported by the local genomic context database.
Genomic interval71 530-72 690 nt1 161 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span71 530-73 327 ntGCF_900243205::NZ_OEZU01000007.1::G00012

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900243205::NZ_OEZU01000007.1::G00012

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_OEZU01000007.1All displayed genes belong to this local TCS context.
Neighborhood span71 530-73 327 nt1 798 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
71 530 nt73 327 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DBQ24_RS00545GCF_900243205#DBQ24_RS00545
RRNarL

72 683-73 327 nt · Forward (+)

RefSeq WP_009889048.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2557601Run 6 · HK · 352 sequences
Representative sequenceGCF_000003215#QAC_RS0206170Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2557601

Simplified PFAM architecture for HKOC_2557601

PFAM domain coverage: 149 / 386 aa (38.6%)

1 aa386 aa
HisKA_3: 187-250 aaHisKA_3HATPase_c: 293-377 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[187-250] | HATPase_c[293-377]
  • Domain count: 2
  • Matched identifier: HKOC_2557601
  • Positioned domains: HisKA_3 187-250 ; HATPase_c 293-377
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0206170

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900243205
AssemblyCH6230 · Scaffoldhaploid
Genome composition4 117 774 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key