Gene detail

B2B75_RS05530

Histidine kinase, Classic

Clostridioides difficile · GCF_900166395

ClassHKTypeClassicLength664 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900166395#B2B75_RS05530Stable P2CS identifier used across views.
GenomeGCF_900166395Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0863328Run 6 · 3 sequences · id 100% · cov 80%
External referencesWP_077746569.1 · MIST4 B2B75_RS05530RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

SBP_bac_3HisKAHATPase_c
Protein length664 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage386 / 664 aa (58.1%)Merged over positioned domains only.
Domain description1 SBP_bac_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa664 aa
SBP_bac_3: 58-278 aa (221 aa)1HisKA: 446-508 aa (63 aa)2HATPase_c: 557-658 aa (102 aa)3
Domain-by-domain annotation3 items
1 SBP_bac_3#1
58-278 aa · 221 aa · 33.3% of protein
Raw tokenSBP_bac_3:58:2.92e-41:278:230:224
2 HisKA#2
446-508 aa · 63 aa · 9.5% of protein
Raw tokenHisKA:446:0.000000000000051:508:63:64
3 HATPase_c#3
557-658 aa · 102 aa · 15.4% of protein
Raw tokenHATPase_c:557:2.5e-23:658:103:109
  • Raw architecture: SBP_bac_3:58:2.92e-41:278:230:224#HisKA:446:0.000000000000051:508:63:64#HATPase_c:557:2.5e-23:658:103:109
  • Domain description: 1 SBP_bac_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900166395::NZ_FUUH01000002.1::G00044
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span17692-21008Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA2239386_01115RefSeq proteinWP_077746569.1
Context group IDGCF_900166395::NZ_FUUH01000002.1::G00044
Context members
B2B75_RS05530B2B75_RS05535
Partner locus tags
B2B75_RS05530B2B75_RS05535
Partner old locus tags
SAMEA2239386_01115SAMEA2239386_01116
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_077746569.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2B75_RS05530Primary locus identifier stored in the genes table.
Old locus tagSAMEA2239386_01115Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUUH01000002.1Sequence record reported by the local genomic context database.
Genomic interval17 692-19 686 nt1 995 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span17 692-21 008 ntGCF_900166395::NZ_FUUH01000002.1::G00044

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900166395::NZ_FUUH01000002.1::G00044

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUUH01000002.1All displayed genes belong to this local TCS context.
Neighborhood span17 692-21 008 nt3 317 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
17 692 nt21 008 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

B2B75_RS05530GCF_900166395#B2B75_RS05530
HKClassicCurrent focus

17 692-19 686 nt · Forward (+)

Old locus SAMEA2239386_01115RefSeq WP_077746569.1
B2B75_RS05535GCF_900166395#B2B75_RS05535
RRNtrC

19 686-21 008 nt · Forward (+)

Old locus SAMEA2239386_01116RefSeq WP_009893260.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0863328Run 6 · HK · 3 sequences
Representative sequenceGCF_038752755#ABCQ02_RS18020Use this link to inspect the representative gene detail.
PFAM architectureSBP_bac_3 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0863328

Simplified PFAM architecture for HKOC_0863328

PFAM domain coverage: 385 / 664 aa (58.0%)

1 aa664 aa
SBP_bac_3: 60-277 aaSBP_bac_3HisKA: 448-509 aaHisKAHATPase_c: 555-659 aaHATPase_c
SBP_bac_3HisKAHATPase_c
  • Simplified architecture: SBP_bac_3 + HisKA + HATPase_c
  • Raw architecture: SBP_bac_3[60-277] | HisKA[448-509] | HATPase_c[555-659]
  • Domain count: 3
  • Matched identifier: HKOC_0863328
  • Positioned domains: SBP_bac_3 60-277 ; HisKA 448-509 ; HATPase_c 555-659
Cluster members and taxonomy
Visualization

Representative gene: GCF_038752755#ABCQ02_RS18020

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900166395
Assembly11670_1#37 · Scaffoldhaploid
Genome composition4 025 541 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 46 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key