Gene detail

B2A51_RS08005

Histidine kinase, Classic

Clostridioides difficile · GCF_900166075

ClassHKTypeClassicLength371 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_900166075#B2A51_RS08005Stable P2CS identifier used across views.
GenomeGCF_900166075Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2676088Run 6 · 404 sequences · id 100% · cov 80%
External referencesWP_009891726.1 · A0AB74R1N1 · MIST4 B2A51_RS08005RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length371 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 371 aa (46.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa371 aa
HisKA: 148-211 aa (64 aa)1HATPase_c: 260-368 aa (109 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
148-211 aa · 64 aa · 17.3% of protein
Raw tokenHisKA:148:0.00000000000008:211:64:64
2 HATPase_c#2
260-368 aa · 109 aa · 29.4% of protein
Raw tokenHATPase_c:260:4.62e-25:368:110:109
  • Raw architecture: HisKA:148:0.00000000000008:211:64:64#HATPase_c:260:4.62e-25:368:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpentadGCF_900166075::NZ_FUTA01000002.1::G00018
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span637599-643324Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA2239417_01618RefSeq proteinWP_009891726.1
Context group IDGCF_900166075::NZ_FUTA01000002.1::G00018
Context members
B2A51_RS08005B2A51_RS08010B2A51_RS08015B2A51_RS08020B2A51_RS08025
Partner locus tags
B2A51_RS08005B2A51_RS08010B2A51_RS08015B2A51_RS08020B2A51_RS08025
Partner old locus tags
SAMEA2239417_01618SAMEA2239417_01619SAMEA2239417_01620SAMEA2239417_01621SAMEA2239417_01622

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009891726.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74R1N1Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74R1N1_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2A51_RS08005Primary locus identifier stored in the genes table.
Old locus tagSAMEA2239417_01618Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUTA01000002.1Sequence record reported by the local genomic context database.
Genomic interval637 599-638 714 nt1 116 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span637 599-643 324 ntGCF_900166075::NZ_FUTA01000002.1::G00018

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900166075::NZ_FUTA01000002.1::G00018

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUTA01000002.1All displayed genes belong to this local TCS context.
Neighborhood span637 599-643 324 nt5 726 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
637 599 nt643 324 nt
Neighborhood gene cards

5 genes in the current local neighborhood.

B2A51_RS08005GCF_900166075#B2A51_RS08005
HKClassicCurrent focus

637 599-638 714 nt · Reverse (-)

Old locus SAMEA2239417_01618RefSeq WP_009891726.1
B2A51_RS08010GCF_900166075#B2A51_RS08010
RROmpR

638 750-639 448 nt · Reverse (-)

Old locus SAMEA2239417_01619RefSeq WP_021363030.1
B2A51_RS08015GCF_900166075#B2A51_RS08015
RROmpR

639 830-640 510 nt · Reverse (-)

Old locus SAMEA2239417_01620RefSeq WP_021363031.1
B2A51_RS08020GCF_900166075#B2A51_RS08020
HKClassic

640 560-642 575 nt · Reverse (-)

Old locus SAMEA2239417_01621RefSeq WP_021363032.1
B2A51_RS08025GCF_900166075#B2A51_RS08025
RROmpR

642 647-643 324 nt · Reverse (-)

Old locus SAMEA2239417_01622RefSeq WP_003417201.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2676088Run 6 · HK · 404 sequences
Representative sequenceGCF_000003215#QAC_RS0216515Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2676088

Simplified PFAM architecture for HKOC_2676088

PFAM domain coverage: 174 / 371 aa (46.9%)

1 aa371 aa
HisKA: 149-213 aaHisKAHATPase_c: 261-369 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[149-213] | HATPase_c[261-369]
  • Domain count: 2
  • Matched identifier: HKOC_2676088
  • Positioned domains: HisKA 149-213 ; HATPase_c 261-369
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0216515

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900166075
Assembly11670_1#69 · Scaffoldhaploid
Genome composition4 068 751 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key