Gene detail

B2A70_RS02420

Histidine kinase, Classic

Clostridioides difficile · GCF_900166005

ClassHKTypeClassicLength436 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900166005#B2A70_RS02420Stable P2CS identifier used across views.
GenomeGCF_900166005Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2113478Run 6 · 38 sequences · id 100% · cov 80%
External referencesWP_021376033.1 · MIST4 B2A70_RS02420RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length436 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage161 / 436 aa (36.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa436 aa
HisKA: 218-278 aa (61 aa)1HATPase_c: 334-433 aa (100 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
218-278 aa · 61 aa · 14.0% of protein
Raw tokenHisKA:218:0.000000000627:278:61:64
2 HATPase_c#2
334-433 aa · 100 aa · 22.9% of protein
Raw tokenHATPase_c:334:4.59e-25:433:100:109
  • Raw architecture: HisKA:218:0.000000000627:278:61:64#HATPase_c:334:4.59e-25:433:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900166005::NZ_FUST01000002.1::G00040
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span187473-189484Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA2239411_00497RefSeq proteinWP_021376033.1
Context group IDGCF_900166005::NZ_FUST01000002.1::G00040
Context members
B2A70_RS02415B2A70_RS02420
Partner locus tags
B2A70_RS02415B2A70_RS02420
Partner old locus tags
SAMEA2239411_00496SAMEA2239411_00497
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021376033.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2A70_RS02420Primary locus identifier stored in the genes table.
Old locus tagSAMEA2239411_00497Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUST01000002.1Sequence record reported by the local genomic context database.
Genomic interval188 174-189 484 nt1 311 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span187 473-189 484 ntGCF_900166005::NZ_FUST01000002.1::G00040

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900166005::NZ_FUST01000002.1::G00040

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUST01000002.1All displayed genes belong to this local TCS context.
Neighborhood span187 473-189 484 nt2 012 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
187 473 nt189 484 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

B2A70_RS02415GCF_900166005#B2A70_RS02415
RROmpR

187 473-188 180 nt · Forward (+)

Old locus SAMEA2239411_00496RefSeq WP_021376003.1
B2A70_RS02420GCF_900166005#B2A70_RS02420
HKClassicCurrent focus

188 174-189 484 nt · Forward (+)

Old locus SAMEA2239411_00497RefSeq WP_021376033.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2113478Run 6 · HK · 38 sequences
Representative sequenceGCF_000449185#QCW_RS12815Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2113478

Simplified PFAM architecture for HKOC_2113478

PFAM domain coverage: 166 / 436 aa (38.1%)

1 aa436 aa
HisKA: 217-278 aaHisKAHATPase_c: 330-433 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[217-278] | HATPase_c[330-433]
  • Domain count: 2
  • Matched identifier: HKOC_2113478
  • Positioned domains: HisKA 217-278 ; HATPase_c 330-433
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449185#QCW_RS12815

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900166005
Assembly11670_1#63 · Scaffoldhaploid
Genome composition4 122 619 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 43 · RR 51CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key