Gene detail

B2A22_RS02325

Histidine kinase, Classic

Clostridioides difficile · GCF_900165975

ClassHKTypeClassicLength425 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900165975#B2A22_RS02325Stable P2CS identifier used across views.
GenomeGCF_900165975Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2216341Run 6 · 39 sequences · id 100% · cov 80%
External referencesWP_032547518.1 · MIST4 B2A22_RS02325RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length425 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage183 / 425 aa (43.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for B2A22_RS02325
Domain-by-domain annotation2 items
1 HisKA#1
196-260 aa · 65 aa · 15.3% of protein
Raw tokenHisKA:196:0.0000000000139:260:65:64
2 HATPase_c#2
307-424 aa · 118 aa · 27.8% of protein
Raw tokenHATPase_c:307:4.23e-19:424:119:109
  • Raw architecture: HisKA:196:0.0000000000139:260:65:64#HATPase_c:307:4.23e-19:424:119:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900165975::NZ_FUSQ01000002.1::G00031
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span170880-172809Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA2239355_00482RefSeq proteinWP_032547518.1
Context group IDGCF_900165975::NZ_FUSQ01000002.1::G00031
Context members
B2A22_RS02320B2A22_RS02325
Partner locus tags
B2A22_RS02320B2A22_RS02325
Partner old locus tags
SAMEA2239355_00481SAMEA2239355_00482
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_032547518.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2A22_RS02325Primary locus identifier stored in the genes table.
Old locus tagSAMEA2239355_00482Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUSQ01000002.1Sequence record reported by the local genomic context database.
Genomic interval171 532-172 809 nt1 278 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span170 880-172 809 ntGCF_900165975::NZ_FUSQ01000002.1::G00031

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900165975::NZ_FUSQ01000002.1::G00031

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUSQ01000002.1All displayed genes belong to this local TCS context.
Neighborhood span170 880-172 809 nt1 930 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
170 880 nt172 809 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

B2A22_RS02320GCF_900165975#B2A22_RS02320
RROmpR

170 880-171 548 nt · Forward (+)

Old locus SAMEA2239355_00481RefSeq WP_021375780.1
B2A22_RS02325GCF_900165975#B2A22_RS02325
HKClassicCurrent focus

171 532-172 809 nt · Forward (+)

Old locus SAMEA2239355_00482RefSeq WP_032547518.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2216341Run 6 · HK · 39 sequences
Representative sequenceGCF_000449185#QCW_RS10720Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2216341

Simplified PFAM architecture for HKOC_2216341

PFAM domain coverage: 179 / 425 aa (42.1%)

1 aa425 aa
HisKA: 197-260 aaHisKAHATPase_c: 308-422 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[197-260] | HATPase_c[308-422]
  • Domain count: 2
  • Matched identifier: HKOC_2216341
  • Positioned domains: HisKA 197-260 ; HATPase_c 308-422
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449185#QCW_RS10720

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900165975
Assembly11670_1#4 · Scaffoldhaploid
Genome composition4 254 923 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 43 · RR 51CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key