Gene detail

B2C15_RS12445

Histidine kinase, Classic

Clostridioides difficile · GCF_900165905

ClassHKTypeClassicLength417 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900165905#B2C15_RS12445Stable P2CS identifier used across views.
GenomeGCF_900165905Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2293768Run 6 · 49 sequences · id 100% · cov 80%
External referencesWP_074048385.1 · MIST4 B2C15_RS12445RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length417 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 417 aa (40.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa417 aa
HisKA: 199-258 aa (60 aa)1HATPase_c: 304-410 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
199-258 aa · 60 aa · 14.4% of protein
Raw tokenHisKA:199:0.00000000119:258:60:64
2 HATPase_c#2
304-410 aa · 107 aa · 25.7% of protein
Raw tokenHATPase_c:304:1.86e-21:410:107:109
  • Raw architecture: HisKA:199:0.00000000119:258:60:64#HATPase_c:304:1.86e-21:410:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900165905::NZ_FUSH01000008.1::G00014
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span176140-178096Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA2239368_02485RefSeq proteinWP_074048385.1
Context group IDGCF_900165905::NZ_FUSH01000008.1::G00014
Context members
B2C15_RS12440B2C15_RS12445
Partner locus tags
B2C15_RS12440B2C15_RS12445
Partner old locus tags
SAMEA2239368_02484SAMEA2239368_02485
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_074048385.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2C15_RS12445Primary locus identifier stored in the genes table.
Old locus tagSAMEA2239368_02485Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUSH01000008.1Sequence record reported by the local genomic context database.
Genomic interval176 843-178 096 nt1 254 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span176 140-178 096 ntGCF_900165905::NZ_FUSH01000008.1::G00014

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900165905::NZ_FUSH01000008.1::G00014

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUSH01000008.1All displayed genes belong to this local TCS context.
Neighborhood span176 140-178 096 nt1 957 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
176 140 nt178 096 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

B2C15_RS12440GCF_900165905#B2C15_RS12440
RROmpR

176 140-176 865 nt · Forward (+)

Old locus SAMEA2239368_02484RefSeq WP_003438649.1
B2C15_RS12445GCF_900165905#B2C15_RS12445
HKClassicCurrent focus

176 843-178 096 nt · Forward (+)

Old locus SAMEA2239368_02485RefSeq WP_074048385.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2293768Run 6 · HK · 49 sequences
Representative sequenceGCF_000448845#QAQ_RS07310Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2293768

Simplified PFAM architecture for HKOC_2293768

PFAM domain coverage: 169 / 417 aa (40.5%)

1 aa417 aa
HisKA: 196-258 aaHisKAHATPase_c: 305-410 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[196-258] | HATPase_c[305-410]
  • Domain count: 2
  • Matched identifier: HKOC_2293768
  • Positioned domains: HisKA 196-258 ; HATPase_c 305-410
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448845#QAQ_RS07310

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900165905
Assembly11670_1#18 · Scaffoldhaploid
Genome composition4 013 977 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 95 · HK 46 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key