Gene detail

B2C10_RS14370

Histidine kinase, Classic

Clostridioides difficile · GCF_900165835

ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_900165835#B2C10_RS14370Stable P2CS identifier used across views.
GenomeGCF_900165835Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0842607Run 6 · 44 sequences · id 100% · cov 80%
External referencesWP_021422693.1 · MIST4 B2C10_RS14370RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa671 aa
HisKA: 449-514 aa (66 aa)1HATPase_c: 565-668 aa (104 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw tokenHisKA:449:0.00000000344:514:66:64
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw tokenHATPase_c:565:4.17e-30:668:104:109
  • Raw architecture: HisKA:449:0.00000000344:514:66:64#HATPase_c:565:4.17e-30:668:104:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpentadGCF_900165835::NZ_FUSB01000005.1::G00026
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span167751-173475Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3375053_02866RefSeq proteinWP_021422693.1
Context group IDGCF_900165835::NZ_FUSB01000005.1::G00026
Context members
B2C10_RS14365B2C10_RS14370B2C10_RS14375B2C10_RS14380B2C10_RS14385
Partner locus tags
B2C10_RS14365B2C10_RS14370B2C10_RS14375B2C10_RS14380B2C10_RS14385
Partner old locus tags
SAMEA3375053_02865SAMEA3375053_02866SAMEA3375053_02867SAMEA3375053_02868SAMEA3375053_02869

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021422693.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2C10_RS14370Primary locus identifier stored in the genes table.
Old locus tagSAMEA3375053_02866Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUSB01000005.1Sequence record reported by the local genomic context database.
Genomic interval168 500-170 515 nt2 016 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span167 751-173 475 ntGCF_900165835::NZ_FUSB01000005.1::G00026

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900165835::NZ_FUSB01000005.1::G00026

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUSB01000005.1All displayed genes belong to this local TCS context.
Neighborhood span167 751-173 475 nt5 725 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
167 751 nt173 475 nt
Neighborhood gene cards

5 genes in the current local neighborhood.

B2C10_RS14365GCF_900165835#B2C10_RS14365
RROmpR

167 751-168 428 nt · Forward (+)

Old locus SAMEA3375053_02865RefSeq WP_003417201.1
B2C10_RS14370GCF_900165835#B2C10_RS14370
HKClassicCurrent focus

168 500-170 515 nt · Forward (+)

Old locus SAMEA3375053_02866RefSeq WP_021422693.1
B2C10_RS14375GCF_900165835#B2C10_RS14375
RROmpR

170 565-171 245 nt · Forward (+)

Old locus SAMEA3375053_02867RefSeq WP_003432361.1
B2C10_RS14380GCF_900165835#B2C10_RS14380
RROmpR

171 626-172 324 nt · Forward (+)

Old locus SAMEA3375053_02868RefSeq WP_021422705.1
B2C10_RS14385GCF_900165835#B2C10_RS14385
HKClassic

172 360-173 475 nt · Forward (+)

Old locus SAMEA3375053_02869RefSeq WP_021397421.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0842607Run 6 · HK · 44 sequences
Representative sequenceGCF_000451765#QSM_RS02260Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0842607

Simplified PFAM architecture for HKOC_0842607

PFAM domain coverage: 170 / 671 aa (25.3%)

1 aa671 aa
HisKA: 450-514 aaHisKAHATPase_c: 563-667 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[450-514] | HATPase_c[563-667]
  • Domain count: 2
  • Matched identifier: HKOC_0842607
  • Positioned domains: HisKA 450-514 ; HATPase_c 563-667
Cluster members and taxonomy
Visualization

Representative gene: GCF_000451765#QSM_RS02260

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900165835
Assembly16852_2#81 · Scaffoldhaploid
Genome composition4 290 919 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 108 · HK 53 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key