Gene detail

B2B56_RS05355

Histidine kinase, Classic

Clostridioides difficile · GCF_900165815

ClassHKTypeClassicLength529 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900165815#B2B56_RS05355Stable P2CS identifier used across views.
GenomeGCF_900165815Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1359670Run 6 · 106 sequences · id 100% · cov 80%
External referencesWP_021361920.1 · A0A381ICQ1 · MIST4 B2B56_RS05355RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length529 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 529 aa (28.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa529 aa
HisKA: 308-374 aa (67 aa)1HATPase_c: 427-512 aa (86 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
308-374 aa · 67 aa · 12.7% of protein
Raw tokenHisKA:308:0.0000000000000165:374:67:64
2 HATPase_c#2
427-512 aa · 86 aa · 16.3% of protein
Raw tokenHATPase_c:427:0.0000000476:512:90:109
  • Raw architecture: HisKA:308:0.0000000000000165:374:67:64#HATPase_c:427:0.0000000476:512:90:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900165815::NZ_FUSA01000002.1::G00054
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span283497-285771Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3375051_01075RefSeq proteinWP_021361920.1
Context group IDGCF_900165815::NZ_FUSA01000002.1::G00054
Context members
B2B56_RS05350B2B56_RS05355
Partner locus tags
B2B56_RS05350B2B56_RS05355
Partner old locus tags
SAMEA3375051_01074SAMEA3375051_01075
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021361920.1Primary protein accession used for annex mappings.
UniProt accessionA0A381ICQ1Primary UniProt accession resolved in the annex database.
UniProt IDA0A381ICQ1_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2B56_RS05355Primary locus identifier stored in the genes table.
Old locus tagSAMEA3375051_01075Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUSA01000002.1Sequence record reported by the local genomic context database.
Genomic interval284 182-285 771 nt1 590 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span283 497-285 771 ntGCF_900165815::NZ_FUSA01000002.1::G00054

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900165815::NZ_FUSA01000002.1::G00054

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUSA01000002.1All displayed genes belong to this local TCS context.
Neighborhood span283 497-285 771 nt2 275 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
283 497 nt285 771 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

B2B56_RS05350GCF_900165815#B2B56_RS05350
RROmpR

283 497-284 213 nt · Forward (+)

Old locus SAMEA3375051_01074RefSeq WP_004454617.1
B2B56_RS05355GCF_900165815#B2B56_RS05355
HKClassicCurrent focus

284 182-285 771 nt · Forward (+)

Old locus SAMEA3375051_01075RefSeq WP_021361920.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1359670Run 6 · HK · 106 sequences
Representative sequenceGCF_000009205#CD630_RS12495Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1359670

Simplified PFAM architecture for HKOC_1359670

PFAM domain coverage: 191 / 529 aa (36.1%)

1 aa529 aa
HAMP: 254-294 aaHAMPHisKA: 309-374 aaHisKAHATPase_c: 426-509 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[254-294] | HisKA[309-374] | HATPase_c[426-509]
  • Domain count: 3
  • Matched identifier: HKOC_1359670
  • Positioned domains: HAMP 254-294 ; HisKA 309-374 ; HATPase_c 426-509
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS12495

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900165815
Assembly16852_2#79 · Scaffoldhaploid
Genome composition4 258 035 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 109 · HK 52 · RR 57CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key