Gene detail

B2B07_RS13045

Histidine kinase, Classic

Clostridioides difficile · GCF_900165615

ClassHKTypeClassicLength474 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900165615#B2B07_RS13045Stable P2CS identifier used across views.
GenomeGCF_900165615Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1680787Run 6 · 15 sequences · id 100% · cov 80%
External referencesWP_077699685.1 · MIST4 B2B07_RS13045RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length474 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 474 aa (53.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa474 aa
HAMP: 161-238 aa (78 aa)1HisKA: 250-315 aa (66 aa)2HATPase_c: 365-471 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
161-238 aa · 78 aa · 16.5% of protein
Raw tokenHAMP:161:0.0000000156:238:78:69
2 HisKA#2
250-315 aa · 66 aa · 13.9% of protein
Raw tokenHisKA:250:0.00000000187:315:66:64
3 HATPase_c#3
365-471 aa · 107 aa · 22.6% of protein
Raw tokenHATPase_c:365:2.24e-26:471:107:109
  • Raw architecture: HAMP:161:0.0000000156:238:78:69#HisKA:250:0.00000000187:315:66:64#HATPase_c:365:2.24e-26:471:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900165615::NZ_FURG01000006.1::G00030
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span94184-96319Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3375005_02630RefSeq proteinWP_077699685.1
Context group IDGCF_900165615::NZ_FURG01000006.1::G00030
Context members
B2B07_RS13045B2B07_RS13050
Partner locus tags
B2B07_RS13045B2B07_RS13050
Partner old locus tags
SAMEA3375005_02630SAMEA3375005_02631
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_077699685.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2B07_RS13045Primary locus identifier stored in the genes table.
Old locus tagSAMEA3375005_02630Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FURG01000006.1Sequence record reported by the local genomic context database.
Genomic interval94 184-95 608 nt1 425 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span94 184-96 319 ntGCF_900165615::NZ_FURG01000006.1::G00030

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900165615::NZ_FURG01000006.1::G00030

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FURG01000006.1All displayed genes belong to this local TCS context.
Neighborhood span94 184-96 319 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
94 184 nt96 319 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

B2B07_RS13045GCF_900165615#B2B07_RS13045
HKClassicCurrent focus

94 184-95 608 nt · Reverse (-)

Old locus SAMEA3375005_02630RefSeq WP_077699685.1
B2B07_RS13050GCF_900165615#B2B07_RS13050
RROmpR

95 627-96 319 nt · Reverse (-)

Old locus SAMEA3375005_02631RefSeq WP_038810830.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1680787Run 6 · HK · 15 sequences
Representative sequenceGCF_021532205#I6E59_RS08610Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1680787

Simplified PFAM architecture for HKOC_1680787

PFAM domain coverage: 223 / 474 aa (47.0%)

1 aa474 aa
HAMP: 188-238 aaHAMPHisKA: 251-315 aaHisKAHATPase_c: 365-471 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[188-238] | HisKA[251-315] | HATPase_c[365-471]
  • Domain count: 3
  • Matched identifier: HKOC_1680787
  • Positioned domains: HAMP 188-238 ; HisKA 251-315 ; HATPase_c 365-471
Cluster members and taxonomy
Visualization

Representative gene: GCF_021532205#I6E59_RS08610

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900165615
Assembly16852_2#33 · Scaffoldhaploid
Genome composition4 079 714 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 104 · HK 49 · RR 54CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key