Gene detail

B2B07_RS09180

Histidine kinase, Classic

Clostridioides difficile · GCF_900165615

ClassHKTypeClassicLength440 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900165615#B2B07_RS09180Stable P2CS identifier used across views.
GenomeGCF_900165615Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2077589Run 6 · 11 sequences · id 100% · cov 80%
External referencesWP_077710377.1 · MIST4 B2B07_RS09180RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length440 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage218 / 440 aa (49.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa440 aa
HAMP: 156-222 aa (67 aa)1HisKA: 233-291 aa (59 aa)2HATPase_c: 348-439 aa (92 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
156-222 aa · 67 aa · 15.2% of protein
Raw tokenHAMP:156:0.000000000553:222:70:69
2 HisKA#2
233-291 aa · 59 aa · 13.4% of protein
Raw tokenHisKA:233:0.000000000177:291:59:64
3 HATPase_c#3
348-439 aa · 92 aa · 20.9% of protein
Raw tokenHATPase_c:348:0.0000000173:439:108:109
  • Raw architecture: HAMP:156:0.000000000553:222:70:69#HisKA:233:0.000000000177:291:59:64#HATPase_c:348:0.0000000173:439:108:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900165615::NZ_FURG01000003.1::G00040
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span583179-585198Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3375005_01861RefSeq proteinWP_077710377.1
Context group IDGCF_900165615::NZ_FURG01000003.1::G00040
Context members
B2B07_RS09175B2B07_RS09180
Partner locus tags
B2B07_RS09175B2B07_RS09180
Partner old locus tags
SAMEA3375005_01860SAMEA3375005_01861
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_077710377.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2B07_RS09180Primary locus identifier stored in the genes table.
Old locus tagSAMEA3375005_01861Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FURG01000003.1Sequence record reported by the local genomic context database.
Genomic interval583 876-585 198 nt1 323 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span583 179-585 198 ntGCF_900165615::NZ_FURG01000003.1::G00040

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900165615::NZ_FURG01000003.1::G00040

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FURG01000003.1All displayed genes belong to this local TCS context.
Neighborhood span583 179-585 198 nt2 020 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
583 179 nt585 198 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

B2B07_RS09175GCF_900165615#B2B07_RS09175
RROmpR

583 179-583 883 nt · Forward (+)

Old locus SAMEA3375005_01860RefSeq WP_003426384.1
B2B07_RS09180GCF_900165615#B2B07_RS09180
HKClassicCurrent focus

583 876-585 198 nt · Forward (+)

Old locus SAMEA3375005_01861RefSeq WP_077710377.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2077589Run 6 · HK · 11 sequences
Representative sequenceGCF_025534015#H3U72_RS06835Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c_53 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2077589

Simplified PFAM architecture for HKOC_2077589

PFAM domain coverage: 169 / 440 aa (38.4%)

1 aa440 aa
HAMP: 177-221 aaHAMPHisKA: 235-291 aaHisKAHATPase_c_5: 370-436 aaHATPase_c_5
HAMPHisKAHATPase_c_5
  • Simplified architecture: HAMP + HisKA + HATPase_c_5
  • Raw architecture: HAMP[177-221] | HisKA[235-291] | HATPase_c_5[370-436]
  • Domain count: 3
  • Matched identifier: HKOC_2077589
  • Positioned domains: HAMP 177-221 ; HisKA 235-291 ; HATPase_c_5 370-436
Cluster members and taxonomy
Visualization

Representative gene: GCF_025534015#H3U72_RS06835

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900165615
Assembly16852_2#33 · Scaffoldhaploid
Genome composition4 079 714 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 104 · HK 49 · RR 54CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key