Gene detail

B2B39_RS14855

Histidine kinase, Classic

Clostridioides difficile · GCF_900165575

ClassHKTypeClassicLength305 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900165575#B2B39_RS14855Stable P2CS identifier used across views.
GenomeGCF_900165575Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2882373Run 6 · 6 sequences · id 100% · cov 80%
External referencesWP_070421136.1 · MIST4 B2B39_RS14855RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length305 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage226 / 305 aa (74.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for B2B39_RS14855
Domain-by-domain annotation3 items
1 HAMP#1
4-56 aa · 53 aa · 17.4% of protein
Raw tokenHAMP:4:0.0000187:56:53:69
2 HisKA#2
85-150 aa · 66 aa · 21.6% of protein
Raw tokenHisKA:85:0.0000000906:150:66:64
3 HATPase_c#3
197-303 aa · 107 aa · 35.1% of protein
Raw tokenHATPase_c:197:1.66e-30:303:107:109
  • Raw architecture: HAMP:4:0.0000187:56:53:69#HisKA:85:0.0000000906:150:66:64#HATPase_c:197:1.66e-30:303:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900165575::NZ_FURC01000009.1::G00031
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span61912-63528Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3375000_02978RefSeq proteinWP_070421136.1
Context group IDGCF_900165575::NZ_FURC01000009.1::G00031
Context members
B2B39_RS14855B2B39_RS14860
Partner locus tags
B2B39_RS14855B2B39_RS14860
Partner old locus tags
SAMEA3375000_02978SAMEA3375000_02979
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_070421136.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2B39_RS14855Primary locus identifier stored in the genes table.
Old locus tagSAMEA3375000_02978Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FURC01000009.1Sequence record reported by the local genomic context database.
Genomic interval61 912-62 829 nt918 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span61 912-63 528 ntGCF_900165575::NZ_FURC01000009.1::G00031

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900165575::NZ_FURC01000009.1::G00031

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FURC01000009.1All displayed genes belong to this local TCS context.
Neighborhood span61 912-63 528 nt1 617 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
61 912 nt63 528 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

B2B39_RS14855GCF_900165575#B2B39_RS14855
HKClassicCurrent focus

61 912-62 829 nt · Reverse (-)

Old locus SAMEA3375000_02978RefSeq WP_070421136.1
B2B39_RS14860GCF_900165575#B2B39_RS14860
RROmpR

62 836-63 528 nt · Reverse (-)

Old locus SAMEA3375000_02979RefSeq WP_021371113.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2882373Run 6 · HK · 6 sequences
Representative sequenceGCF_003482065#CDIF28666_RS01640Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2882373

Simplified PFAM architecture for HKOC_2882373

PFAM domain coverage: 169 / 305 aa (55.4%)

1 aa305 aa
HisKA: 85-148 aaHisKAHATPase_c: 199-303 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[85-148] | HATPase_c[199-303]
  • Domain count: 2
  • Matched identifier: HKOC_2882373
  • Positioned domains: HisKA 85-148 ; HATPase_c 199-303
Cluster members and taxonomy
Visualization

Representative gene: GCF_003482065#CDIF28666_RS01640

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900165575
Assembly16852_2#28 · Scaffoldhaploid
Genome composition4 144 567 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 107 · HK 51 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key