Gene detail

B2A46_RS02305

Histidine kinase, Classic

Clostridioides difficile · GCF_900165485

ClassHKTypeClassicLength343 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900165485#B2A46_RS02305Stable P2CS identifier used across views.
GenomeGCF_900165485Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2828068Run 6 · 34 sequences · id 100% · cov 80%
External referencesWP_022618024.1 · MIST4 B2A46_RS02305RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length343 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 343 aa (48.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa343 aa
HisKA: 124-189 aa (66 aa)1HATPase_c: 241-341 aa (101 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
124-189 aa · 66 aa · 19.2% of protein
Raw tokenHisKA:124:0.000000261:189:66:64
2 HATPase_c#2
241-341 aa · 101 aa · 29.4% of protein
Raw tokenHATPase_c:241:2.73e-24:341:101:109
  • Raw architecture: HisKA:124:0.000000261:189:66:64#HATPase_c:241:2.73e-24:341:101:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900165485::NZ_FUQT01000001.1::G00047
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span483984-485691Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3374984_00470RefSeq proteinWP_022618024.1
Context group IDGCF_900165485::NZ_FUQT01000001.1::G00047
Context members
B2A46_RS02300B2A46_RS02305
Partner locus tags
B2A46_RS02300B2A46_RS02305
Partner old locus tags
SAMEA3374984_00469SAMEA3374984_00470
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_022618024.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2A46_RS02305Primary locus identifier stored in the genes table.
Old locus tagSAMEA3374984_00470Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUQT01000001.1Sequence record reported by the local genomic context database.
Genomic interval484 660-485 691 nt1 032 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span483 984-485 691 ntGCF_900165485::NZ_FUQT01000001.1::G00047

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900165485::NZ_FUQT01000001.1::G00047

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUQT01000001.1All displayed genes belong to this local TCS context.
Neighborhood span483 984-485 691 nt1 708 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
483 984 nt485 691 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

B2A46_RS02300GCF_900165485#B2A46_RS02300
RROmpR

483 984-484 670 nt · Forward (+)

Old locus SAMEA3374984_00469RefSeq WP_022618023.1
B2A46_RS02305GCF_900165485#B2A46_RS02305
HKClassicCurrent focus

484 660-485 691 nt · Forward (+)

Old locus SAMEA3374984_00470RefSeq WP_022618024.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2828068Run 6 · HK · 34 sequences
Representative sequenceGCF_000531385#BN169_RS11575Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2828068

Simplified PFAM architecture for HKOC_2828068

PFAM domain coverage: 173 / 343 aa (50.4%)

1 aa343 aa
HisKA: 124-189 aaHisKAHATPase_c: 236-342 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[124-189] | HATPase_c[236-342]
  • Domain count: 2
  • Matched identifier: HKOC_2828068
  • Positioned domains: HisKA 124-189 ; HATPase_c 236-342
Cluster members and taxonomy
Visualization

Representative gene: GCF_000531385#BN169_RS11575

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900165485
Assembly16852_2#12 · Scaffoldhaploid
Genome composition4 593 015 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 48 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key