Gene detail

B2C32_RS04415

Histidine kinase, Classic

Clostridioides difficile · GCF_900165435

ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900165435#B2C32_RS04415Stable P2CS identifier used across views.
GenomeGCF_900165435Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1747750Run 6 · 397 sequences · id 100% · cov 80%
External referencesWP_009902713.1 · A0A9Q9TTP8 · MIST4 B2C32_RS04415RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage242 / 467 aa (51.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa467 aa
HAMP: 166-232 aa (67 aa)1HisKA: 245-312 aa (68 aa)2HATPase_c: 359-465 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
166-232 aa · 67 aa · 14.3% of protein
Raw tokenHAMP:166:0.00000389:232:69:69
2 HisKA#2
245-312 aa · 68 aa · 14.6% of protein
Raw tokenHisKA:245:0.0000000000000205:312:68:64
3 HATPase_c#3
359-465 aa · 107 aa · 22.9% of protein
Raw tokenHATPase_c:359:1.79e-26:465:108:109
  • Raw architecture: HAMP:166:0.00000389:232:69:69#HisKA:245:0.0000000000000205:312:68:64#HATPase_c:359:1.79e-26:465:108:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900165435::NZ_FUQM01000001.1::G00047
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span940675-942807Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3375159_00888RefSeq proteinWP_009902713.1
Context group IDGCF_900165435::NZ_FUQM01000001.1::G00047
Context members
B2C32_RS04415B2C32_RS04420
Partner locus tags
B2C32_RS04415B2C32_RS04420
Partner old locus tags
SAMEA3375159_00888SAMEA3375159_00889
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009902713.1Primary protein accession used for annex mappings.
UniProt accessionA0A9Q9TTP8Primary UniProt accession resolved in the annex database.
UniProt IDA0A9Q9TTP8_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2C32_RS04415Primary locus identifier stored in the genes table.
Old locus tagSAMEA3375159_00888Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUQM01000001.1Sequence record reported by the local genomic context database.
Genomic interval940 675-942 078 nt1 404 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span940 675-942 807 ntGCF_900165435::NZ_FUQM01000001.1::G00047

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900165435::NZ_FUQM01000001.1::G00047

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUQM01000001.1All displayed genes belong to this local TCS context.
Neighborhood span940 675-942 807 nt2 133 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
940 675 nt942 807 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

B2C32_RS04415GCF_900165435#B2C32_RS04415
HKClassicCurrent focus

940 675-942 078 nt · Reverse (-)

Old locus SAMEA3375159_00888RefSeq WP_009902713.1
B2C32_RS04420GCF_900165435#B2C32_RS04420
RROmpR

942 082-942 807 nt · Reverse (-)

Old locus SAMEA3375159_00889RefSeq WP_021360569.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1747750Run 6 · HK · 397 sequences
Representative sequenceGCF_000155025#UAB_RS0209575Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1747750

Simplified PFAM architecture for HKOC_1747750

PFAM domain coverage: 172 / 467 aa (36.8%)

1 aa467 aa
HisKA: 245-309 aaHisKAHATPase_c: 359-465 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-309] | HATPase_c[359-465]
  • Domain count: 2
  • Matched identifier: HKOC_1747750
  • Positioned domains: HisKA 245-309 ; HATPase_c 359-465
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155025#UAB_RS0209575

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900165435
Assembly16780_8#93 · Scaffoldhaploid
Genome composition4 280 213 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 108 · HK 53 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key