1 HAMP#1
212-279 aa · 68 aa · 13.7% of protein
Raw token
HAMP:212:0.0000061:279:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
B2C43_RS09310
Histidine kinase, Classic
Clostridioides difficile · GCF_900165085
ClassHKTypeClassicLength495 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900165085#B2C43_RS09310Stable P2CS identifier used across views.
GenomeGCF_900165085Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length495 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 495 aa (46.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa495 aa
Domain-by-domain annotation3 items
2 HisKA#2
289-347 aa · 59 aa · 11.9% of protein
Raw token
HisKA:289:3.36e-17:347:59:643 HATPase_c#3
395-495 aa · 101 aa · 20.4% of protein
Raw token
HATPase_c:395:2.97e-27:495:106:109- Raw architecture: HAMP:212:0.0000061:279:68:69#HisKA:289:3.36e-17:347:59:64#HATPase_c:395:2.97e-27:495:106:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_900165085::NZ_FUPF01000002.1::G00010
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span29014-31207Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3375099_01874RefSeq proteinWP_165472501.1
Context group ID
GCF_900165085::NZ_FUPF01000002.1::G00010Context members
B2C43_RS09310B2C43_RS09315
Partner locus tags
B2C43_RS09310B2C43_RS09315
Partner old locus tags
SAMEA3375099_01874SAMEA3375099_01875
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_165472501.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagB2C43_RS09310Primary locus identifier stored in the genes table.
Old locus tagSAMEA3375099_01874Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUPF01000002.1Sequence record reported by the local genomic context database.
Genomic interval29 014-30 501 nt1 488 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span29 014-31 207 ntGCF_900165085::NZ_FUPF01000002.1::G00010
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_900165085::NZ_FUPF01000002.1::G00010Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUPF01000002.1All displayed genes belong to this local TCS context.
Neighborhood span29 014-31 207 nt2 194 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
29 014 nt31 207 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
B2C43_RS09310GCF_900165085#B2C43_RS09310
HKClassicCurrent focus
29 014-30 501 nt · Reverse (-)
B2C43_RS09315GCF_900165085#B2C43_RS09315
RROmpR
30 503-31 207 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_002301405#BGU19_RS18840Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1505212
Simplified PFAM architecture for HKOC_1505212
PFAM domain coverage: 161 / 495 aa (32.5%)
1 aa495 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[287-347] | HATPase_c[395-494]
- Domain count: 2
- Matched identifier: HKOC_1505212
- Positioned domains: HisKA 287-347 ; HATPase_c 395-494
Cluster members and taxonomy
Representative gene: GCF_002301405#BGU19_RS18840
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_900165085
Assembly16780_8#33 · Scaffoldhaploid
Genome composition4 231 324 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 52CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key