Gene detail

B2A64_RS01425

Histidine kinase, Classic

Clostridioides difficile · GCF_900165045

ClassHKTypeClassicLength686 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900165045#B2A64_RS01425Stable P2CS identifier used across views.
GenomeGCF_900165045Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0800915Run 6 · 909 sequences · id 100% · cov 80%
External referencesWP_009897457.1 · A0AB74Q9S7 · MIST4 B2A64_RS01425RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length686 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage162 / 686 aa (23.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for B2A64_RS01425
Domain-by-domain annotation2 items
1 HisKA#1
457-524 aa · 68 aa · 9.9% of protein
Raw tokenHisKA:457:0.0000000000000203:524:68:64
2 HATPase_c#2
570-663 aa · 94 aa · 13.7% of protein
Raw tokenHATPase_c:570:0.00000000000196:663:98:109
  • Raw architecture: HisKA:457:0.0000000000000203:524:68:64#HATPase_c:570:0.00000000000196:663:98:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900165045::NZ_FUPB01000001.1::G00033
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span320053-323001Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3375069_00288RefSeq proteinWP_009897457.1
Context group IDGCF_900165045::NZ_FUPB01000001.1::G00033
Context members
B2A64_RS01425B2A64_RS01435
Partner locus tags
B2A64_RS01425B2A64_RS01435
Partner old locus tags
SAMEA3375069_00288SAMEA3375069_00289
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009897457.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74Q9S7Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74Q9S7_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2A64_RS01425Primary locus identifier stored in the genes table.
Old locus tagSAMEA3375069_00288Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUPB01000001.1Sequence record reported by the local genomic context database.
Genomic interval320 053-322 113 nt2 061 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span320 053-323 001 ntGCF_900165045::NZ_FUPB01000001.1::G00033

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900165045::NZ_FUPB01000001.1::G00033

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUPB01000001.1All displayed genes belong to this local TCS context.
Neighborhood span320 053-323 001 nt2 949 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
320 053 nt323 001 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

B2A64_RS01425GCF_900165045#B2A64_RS01425
HKClassicCurrent focus

320 053-322 113 nt · Reverse (-)

Old locus SAMEA3375069_00288RefSeq WP_009897457.1
B2A64_RS01435GCF_900165045#B2A64_RS01435
RROmpR

322 309-323 001 nt · Reverse (-)

Old locus SAMEA3375069_00289RefSeq WP_004454566.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0800915Run 6 · HK · 909 sequences
Representative sequenceGCF_000009205#CD630_RS12360Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0800915

Simplified PFAM architecture for HKOC_0800915

PFAM domain coverage: 160 / 686 aa (23.3%)

1 aa686 aa
HisKA: 457-524 aaHisKAHATPase_c: 571-662 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[457-524] | HATPase_c[571-662]
  • Domain count: 2
  • Matched identifier: HKOC_0800915
  • Positioned domains: HisKA 457-524 ; HATPase_c 571-662
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS12360

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900165045
Assembly16780_8#3 · Scaffoldhaploid
Genome composition4 359 935 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 47 · RR 51CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key