Gene detail

B2C59_RS07590

Histidine kinase, Classic

Clostridioides difficile · GCF_900165035

ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContexttriad
Gene IDGCF_900165035#B2C59_RS07590Stable P2CS identifier used across views.
GenomeGCF_900165035Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0842594Run 6 · 427 sequences · id 100% · cov 80%
External referencesWP_021364827.1 · A0AAN6A5L1 · MIST4 B2C59_RS07590RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa671 aa
HisKA: 449-514 aa (66 aa)1HATPase_c: 565-668 aa (104 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw tokenHisKA:449:0.00000000352:514:66:64
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw tokenHATPase_c:565:4.04e-30:668:104:109
  • Raw architecture: HisKA:449:0.00000000352:514:66:64#HATPase_c:565:4.04e-30:668:104:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labeltriadGCF_900165035::NZ_FUPA01000003.1::G00010
Group size33 locus tags listed below.
HK / RR1 / 2Counts resolved for the local TCS neighborhood.
Context span65488-68982Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3375068_01508RefSeq proteinWP_021364827.1
Context group IDGCF_900165035::NZ_FUPA01000003.1::G00010
Context members
B2C59_RS07585B2C59_RS07590B2C59_RS07595
Partner locus tags
B2C59_RS07585B2C59_RS07590B2C59_RS07595
Partner old locus tags
SAMEA3375068_01507SAMEA3375068_01508SAMEA3375068_01509

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021364827.1Primary protein accession used for annex mappings.
UniProt accessionA0AAN6A5L1Primary UniProt accession resolved in the annex database.
UniProt IDA0AAN6A5L1_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2C59_RS07590Primary locus identifier stored in the genes table.
Old locus tagSAMEA3375068_01508Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUPA01000003.1Sequence record reported by the local genomic context database.
Genomic interval66 237-68 252 nt2 016 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span65 488-68 982 ntGCF_900165035::NZ_FUPA01000003.1::G00010

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900165035::NZ_FUPA01000003.1::G00010

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labeltriadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUPA01000003.1All displayed genes belong to this local TCS context.
Neighborhood span65 488-68 982 nt3 495 nt
Members31 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
65 488 nt68 982 nt
Neighborhood gene cards

3 genes in the current local neighborhood.

B2C59_RS07585GCF_900165035#B2C59_RS07585
RROmpR

65 488-66 165 nt · Forward (+)

Old locus SAMEA3375068_01507RefSeq WP_003417201.1
B2C59_RS07590GCF_900165035#B2C59_RS07590
HKClassicCurrent focus

66 237-68 252 nt · Forward (+)

Old locus SAMEA3375068_01508RefSeq WP_021364827.1
B2C59_RS07595GCF_900165035#B2C59_RS07595
RROmpR

68 302-68 982 nt · Forward (+)

Old locus SAMEA3375068_01509RefSeq WP_003432361.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0842594Run 6 · HK · 427 sequences
Representative sequenceGCF_000448745#QC1_RS16905Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0842594

Simplified PFAM architecture for HKOC_0842594

PFAM domain coverage: 170 / 671 aa (25.3%)

1 aa671 aa
HisKA: 450-514 aaHisKAHATPase_c: 563-667 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[450-514] | HATPase_c[563-667]
  • Domain count: 2
  • Matched identifier: HKOC_0842594
  • Positioned domains: HisKA 450-514 ; HATPase_c 563-667
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448745#QC1_RS16905

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900165035
Assembly16780_8#2 · Scaffoldhaploid
Genome composition4 205 282 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 46 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key