Gene detail

B2C01_RS04725

Histidine kinase, Classic

Clostridioides difficile · GCF_900164995

ClassHKTypeClassicLength476 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900164995#B2C01_RS04725Stable P2CS identifier used across views.
GenomeGCF_900164995Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1663820Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_418657955.1 · MIST4 B2C01_RS04725RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length476 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage165 / 476 aa (34.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa476 aa
HisKA: 258-320 aa (63 aa)1HATPase_c: 369-470 aa (102 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
258-320 aa · 63 aa · 13.2% of protein
Raw tokenHisKA:258:0.000000000000053:320:63:64
2 HATPase_c#2
369-470 aa · 102 aa · 21.4% of protein
Raw tokenHATPase_c:369:4.56e-23:470:103:109
  • Raw architecture: HisKA:258:0.000000000000053:320:63:64#HATPase_c:369:4.56e-23:470:103:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900164995::NZ_FUOX01000001.1::G00059
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1050350-1053066Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3375059_00961RefSeq proteinWP_418657955.1
Context group IDGCF_900164995::NZ_FUOX01000001.1::G00059
Context members
B2C01_RS04720B2C01_RS04725
Partner locus tags
B2C01_RS04720B2C01_RS04725
Partner old locus tags
SAMEA3375059_00960SAMEA3375059_00961
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_418657955.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2C01_RS04725Primary locus identifier stored in the genes table.
Old locus tagSAMEA3375059_00961Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUOX01000001.1Sequence record reported by the local genomic context database.
Genomic interval1 051 672-1 053 066 nt1 395 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 050 350-1 053 066 ntGCF_900164995::NZ_FUOX01000001.1::G00059

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900164995::NZ_FUOX01000001.1::G00059

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUOX01000001.1All displayed genes belong to this local TCS context.
Neighborhood span1 050 350-1 053 066 nt2 717 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 050 350 nt1 053 066 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

B2C01_RS04720GCF_900164995#B2C01_RS04720
RRNtrC

1 050 350-1 051 672 nt · Reverse (-)

Old locus SAMEA3375059_00960RefSeq WP_004454409.1
B2C01_RS04725GCF_900164995#B2C01_RS04725
HKClassicCurrent focus

1 051 672-1 053 066 nt · Reverse (-)

Old locus SAMEA3375059_00961RefSeq WP_418657955.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1663820Run 6 · HK · 1 sequences
Representative sequenceGCF_900164995#B2C01_RS04725The current gene is the representative for this cluster.
PFAM architectureSBP_bac_3 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1663820

Simplified PFAM architecture for HKOC_1663820

PFAM domain coverage: 248 / 476 aa (52.1%)

1 aa476 aa
SBP_bac_3: 9-89 aaSBP_bac_3HisKA: 260-321 aaHisKAHATPase_c: 367-471 aaHATPase_c
SBP_bac_3HisKAHATPase_c
  • Simplified architecture: SBP_bac_3 + HisKA + HATPase_c
  • Raw architecture: SBP_bac_3[9-89] | HisKA[260-321] | HATPase_c[367-471]
  • Domain count: 3
  • Matched identifier: HKOC_1663820
  • Positioned domains: SBP_bac_3 9-89 ; HisKA 260-321 ; HATPase_c 367-471
Cluster members and taxonomy
Visualization

Representative gene: GCF_900164995#B2C01_RS04725

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900164995
Assembly16852_2#87 · Scaffoldhaploid
Genome composition4 523 817 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 50 · RR 54CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key