Gene detail

B2C31_RS00770

Histidine kinase, Classic

Clostridioides difficile · GCF_900164895

ClassHKTypeClassicLength425 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900164895#B2C31_RS00770Stable P2CS identifier used across views.
GenomeGCF_900164895Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2215984Run 6 · 335 sequences · id 100% · cov 80%
External referencesWP_009890242.1 · A0A0H3N4E5 · MIST4 B2C31_RS00770RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length425 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage183 / 425 aa (43.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa425 aa
HisKA: 196-260 aa (65 aa)1HATPase_c: 307-424 aa (118 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
196-260 aa · 65 aa · 15.3% of protein
Raw tokenHisKA:196:0.0000000000151:260:65:64
2 HATPase_c#2
307-424 aa · 118 aa · 27.8% of protein
Raw tokenHATPase_c:307:2.03e-18:424:119:109
  • Raw architecture: HisKA:196:0.0000000000151:260:65:64#HATPase_c:307:2.03e-18:424:119:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900164895::NZ_FUOL01000001.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span170250-172179Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3375041_00156RefSeq proteinWP_009890242.1
Context group IDGCF_900164895::NZ_FUOL01000001.1::G00012
Context members
B2C31_RS00765B2C31_RS00770
Partner locus tags
B2C31_RS00765B2C31_RS00770
Partner old locus tags
SAMEA3375041_00155SAMEA3375041_00156
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009890242.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N4E5Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N4E5_CLODCDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2C31_RS00770Primary locus identifier stored in the genes table.
Old locus tagSAMEA3375041_00156Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUOL01000001.1Sequence record reported by the local genomic context database.
Genomic interval170 902-172 179 nt1 278 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span170 250-172 179 ntGCF_900164895::NZ_FUOL01000001.1::G00012

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900164895::NZ_FUOL01000001.1::G00012

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUOL01000001.1All displayed genes belong to this local TCS context.
Neighborhood span170 250-172 179 nt1 930 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
170 250 nt172 179 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

B2C31_RS00765GCF_900164895#B2C31_RS00765
RROmpR

170 250-170 918 nt · Forward (+)

Old locus SAMEA3375041_00155RefSeq WP_003424455.1
B2C31_RS00770GCF_900164895#B2C31_RS00770
HKClassicCurrent focus

170 902-172 179 nt · Forward (+)

Old locus SAMEA3375041_00156RefSeq WP_009890242.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2215984Run 6 · HK · 335 sequences
Representative sequenceGCF_000003215#QAC_RS0210660Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2215984

Simplified PFAM architecture for HKOC_2215984

PFAM domain coverage: 179 / 425 aa (42.1%)

1 aa425 aa
HisKA: 197-260 aaHisKAHATPase_c: 308-422 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[197-260] | HATPase_c[308-422]
  • Domain count: 2
  • Matched identifier: HKOC_2215984
  • Positioned domains: HisKA 197-260 ; HATPase_c 308-422
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0210660

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900164895
Assembly16852_2#69 · Scaffoldhaploid
Genome composition4 320 124 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 45 · RR 50CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key