Gene detail

B2B74_RS10965

Histidine kinase, Classic

Clostridioides difficile · GCF_900164665

ClassHKTypeClassicLength429 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900164665#B2B74_RS10965Stable P2CS identifier used across views.
GenomeGCF_900164665Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2180665Run 6 · 12 sequences · id 100% · cov 80%
External referencesWP_200799877.1 · MIST4 B2B74_RS10965RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length429 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage177 / 429 aa (41.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa429 aa
HisKA: 209-274 aa (66 aa)1HATPase_c: 319-429 aa (111 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
209-274 aa · 66 aa · 15.4% of protein
Raw tokenHisKA:209:0.00000000000000272:274:66:64
2 HATPase_c#2
319-429 aa · 111 aa · 25.9% of protein
Raw tokenHATPase_c:319:6.35e-22:429:111:109
  • Raw architecture: HisKA:209:0.00000000000000272:274:66:64#HATPase_c:319:6.35e-22:429:111:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900164665::NZ_FUNP01000003.1::G00025
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span18400-20414Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3374988_02192RefSeq proteinWP_200799877.1
Context group IDGCF_900164665::NZ_FUNP01000003.1::G00025
Context members
B2B74_RS10960B2B74_RS10965
Partner locus tags
B2B74_RS10960B2B74_RS10965
Partner old locus tags
SAMEA3374988_02191SAMEA3374988_02192
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_200799877.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2B74_RS10965Primary locus identifier stored in the genes table.
Old locus tagSAMEA3374988_02192Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUNP01000003.1Sequence record reported by the local genomic context database.
Genomic interval19 125-20 414 nt1 290 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span18 400-20 414 ntGCF_900164665::NZ_FUNP01000003.1::G00025

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900164665::NZ_FUNP01000003.1::G00025

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUNP01000003.1All displayed genes belong to this local TCS context.
Neighborhood span18 400-20 414 nt2 015 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
18 400 nt20 414 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

B2B74_RS10960GCF_900164665#B2B74_RS10960
RROmpR

18 400-19 059 nt · Forward (+)

Old locus SAMEA3374988_02191RefSeq WP_021404737.1
B2B74_RS10965GCF_900164665#B2B74_RS10965
HKClassicCurrent focus

19 125-20 414 nt · Forward (+)

Old locus SAMEA3374988_02192RefSeq WP_200799877.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2180665Run 6 · HK · 12 sequences
Representative sequenceGCF_000531385#BN169_RS02870Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2180665

Simplified PFAM architecture for HKOC_2180665

PFAM domain coverage: 177 / 429 aa (41.3%)

1 aa429 aa
HisKA: 209-274 aaHisKAHATPase_c: 319-429 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[209-274] | HATPase_c[319-429]
  • Domain count: 2
  • Matched identifier: HKOC_2180665
  • Positioned domains: HisKA 209-274 ; HATPase_c 319-429
Cluster members and taxonomy
Visualization

Representative gene: GCF_000531385#BN169_RS02870

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900164665
Assembly16852_2#16 · Scaffoldhaploid
Genome composition4 164 994 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 48 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key