Gene detail

B2B74_RS00430

Histidine kinase, Classic

Clostridioides difficile · GCF_900164665

ClassHKTypeClassicLength429 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900164665#B2B74_RS00430Stable P2CS identifier used across views.
GenomeGCF_900164665Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2180666Run 6 · 18 sequences · id 100% · cov 80%
External referencesWP_022618072.1 · MIST4 B2B74_RS00430RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPPAS_9HisKAHATPase_c
Protein length429 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage340 / 429 aa (79.3%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS_9,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa429 aa
HAMP: 6-74 aa (69 aa)1PAS_9: 96-195 aa (100 aa)2HisKA: 202-268 aa (67 aa)3HATPase_c: 319-422 aa (104 aa)4
Domain-by-domain annotation4 items
1 HAMP#1
6-74 aa · 69 aa · 16.1% of protein
Raw tokenHAMP:6:0.000000251:74:69:69
2 PAS_9#2
96-195 aa · 100 aa · 23.3% of protein
Raw tokenPAS_9:96:0.00000227:195:103:102
3 HisKA#3
202-268 aa · 67 aa · 15.6% of protein
Raw tokenHisKA:202:2.96e-18:268:67:64
4 HATPase_c#4
319-422 aa · 104 aa · 24.2% of protein
Raw tokenHATPase_c:319:3.07e-30:422:104:109
  • Raw architecture: HAMP:6:0.000000251:74:69:69#PAS_9:96:0.00000227:195:103:102#HisKA:202:2.96e-18:268:67:64#HATPase_c:319:3.07e-30:422:104:109
  • Domain description: 1 HAMP,1 PAS_9,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900164665::NZ_FUNP01000001.1::G00030
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span101507-103517Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3374988_00088RefSeq proteinWP_022618072.1
Context group IDGCF_900164665::NZ_FUNP01000001.1::G00030
Context members
B2B74_RS00425B2B74_RS00430
Partner locus tags
B2B74_RS00425B2B74_RS00430
Partner old locus tags
SAMEA3374988_00087SAMEA3374988_00088
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_022618072.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2B74_RS00430Primary locus identifier stored in the genes table.
Old locus tagSAMEA3374988_00088Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUNP01000001.1Sequence record reported by the local genomic context database.
Genomic interval102 228-103 517 nt1 290 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span101 507-103 517 ntGCF_900164665::NZ_FUNP01000001.1::G00030

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900164665::NZ_FUNP01000001.1::G00030

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUNP01000001.1All displayed genes belong to this local TCS context.
Neighborhood span101 507-103 517 nt2 011 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
101 507 nt103 517 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

B2B74_RS00425GCF_900164665#B2B74_RS00425
RROmpR

101 507-102 199 nt · Forward (+)

Old locus SAMEA3374988_00087RefSeq WP_003416112.1
B2B74_RS00430GCF_900164665#B2B74_RS00430
HKClassicCurrent focus

102 228-103 517 nt · Forward (+)

Old locus SAMEA3374988_00088RefSeq WP_022618072.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2180666Run 6 · HK · 18 sequences
Representative sequenceGCF_000531385#BN169_RS13440Use this link to inspect the representative gene detail.
PFAM architectureHAMP + PAS + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2180666

Simplified PFAM architecture for HKOC_2180666

PFAM domain coverage: 324 / 429 aa (75.5%)

1 aa429 aa
HAMP: 30-74 aaHAMPPAS: 87-193 aaPASHisKA: 202-267 aaHisKAHATPase_c: 317-422 aaHATPase_c
HAMPPASHisKAHATPase_c
  • Simplified architecture: HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: HAMP[30-74] | PAS[87-193] | HisKA[202-267] | HATPase_c[317-422]
  • Domain count: 4
  • Matched identifier: HKOC_2180666
  • Positioned domains: HAMP 30-74 ; PAS 87-193 ; HisKA 202-267 ; HATPase_c 317-422
Cluster members and taxonomy
Visualization

Representative gene: GCF_000531385#BN169_RS13440

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900164665
Assembly16852_2#16 · Scaffoldhaploid
Genome composition4 164 994 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 48 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key